Hepatology Highlights

A phase 2 study of filibuvir in combination with pegylated IFN alfa and ribavirin for chronic HCV

Objectives. Filibuvir is a non-nucleoside inhibitor of hepatitis C virus (HCV) polymerase. This study evaluated the safety and efficacy of filibuvir plus pegylated interferon alfa-2a (pegIFN)/ribavirin. Material and meth...

Non-Alcoholic Fatty Liver Disease in Children and Adolescents: Lifestyle Change - a Systematic Review and Meta-Analysis

Introduction and aim. This manuscript seeks to analyze the impact of lifestyle changes on body mass index (BMI), aminotransferases and steatosis in children and adolescents with nonalcoholic fatty liver disease (NAFLD)....

High clinical manifestation rate in an imported outbreak of hepatitis E genotype 1 infection in a German group of travellers returning from India

Background. There are only few reports about travel-associated, imported tropical hepatitis E virus (HEV) genotype 1 infectionswithin Western travellers. We describe the clinical course of a single outbreak of hepatitis...

Clinical course and management of acute hepatitis A infection in adults

Background. Hepatitis A is the most common type of viral hepatitis in Mexico. The change of hepatitis A epidemiology in Mexico from high to intermediate endemicity leads to increasing susceptible adults for severe illn...