PROCEDURE FOR DETERMINATION OF THE MOLECULAR WEIGHT OF CHITOSAN BY VISCOMETRY

Abstract

The aim of this publication is to facilitate the estimation of chitosan molecular weight (MW) in laboratories with no access to sophisticated analytical instruments, by applying the easily accessible and economical capillary viscometry. The procedure of viscosity-average molecular weight (Mv) determination is described in details. The examples provided encompass testing of the experimental procedure for determination of the Mv of chitosan with a low-molecular weight of 7.7 kDa and 88 kDa, after verification with a high-molecular weight polymer (477 kDa). The experimental work demonstrated the importance of the initial concentration of low-MW chitosan for the accurate determination of intrinsic viscosity and, as a consequence, the viscosity-average molecular weight.

Authors and Affiliations

Renata Czechowska-Biskup, Radosław A. Wach, Janusz M. Rosiak, Piotr Ulański

Keywords

Related Articles

THERMAL STABILITY OF CHITOSAN NANOCOMPOSITES CONTAINING TIO2 AND ORGANO-MODIFIED MONTMORILLONITE

The aim of this work was to investigate the effect of different nanoparticles (TiO2 and organically modified montmorillonite MMT) on thermal stability of chitosan thin films (obtained by casting) and to compare with prev...

HAEMOSTATIC, RESORBABLE DRESSING OF NATURAL POLYMERS - HEMOGUARD

Investigations are presented in the preparation of a first aid haemostatic dressing that would exhibit an adequate haemostatic capacity in injuries and surgical wounds, an antibacterial activity to prevent primary and se...

PHYSICOCHEMICAL CHARACTERIZATION AND DISSOLUTION STUDIES OF SOLID DISPERSIONS OF CLOTRIMAZOLE WITH CHITOSAN

The aim of the present study was to increase the solubility of clotrimazole. Among the methods to increase the solubility selected solid dispersions of the drug with the polymer. Chitosan was used as the polymer. Clotrim...

EFFECT OF A HYDROPHILISING SUBSTANCE ON THE VISCOSITY OF GYNAECOLOGICAL GELS CONTAINING LACTIC ACID COMPLEXED WITH CHITOSAN

Thus ensuring a continuous action of a drug also during daily activity time of a patient is a vital question in gynaecological treatment. The main problem in applied therapies is to maintain the continuity of treatment d...

BIOSORPTION/DESORPTION OF CADMIUM(II) AND ZINC (II) FROM AQUEOUS SOLUTIONS BY ACTIVATED SLUDGE IMMOBILIZED ONTO CHITOSAN BEADS

In this study, we evaluated the effectiveness of cadmium and zinc adsorption and desorption from solutions containing single metals and a mixture of metals in the ratio of 1:2 by activated sludge immobilized onto chitosa...

Download PDF file
  • EP ID EP534699
  • DOI 10.15259/PCACD.23.04
  • Views 84
  • Downloads 0

How To Cite

Renata Czechowska-Biskup, Radosław A. Wach, Janusz M. Rosiak, Piotr Ulański (2018). PROCEDURE FOR DETERMINATION OF THE MOLECULAR WEIGHT OF CHITOSAN BY VISCOMETRY. Progress on Chemistry and Application of Chitin and its Derivatives, 0(), 45-54. https://europub.co.uk/articles/-A-534699