Producing of nonwoven materials by electrospinning the biocompatible polymers with chitosan addition
Journal Title: Технологический аудит и резервы производства - Year 2018, Vol 5, Issue 3
Abstract
<p><em>The object of research is biocompatible composite nanofiber nonwoven materials with antiseptic properties, obtained by the electrospinning method. One of the most problematic places is the creation of a nonwoven biocompatible composite material with bactericidal properties; it has not previously been converted into fibers by electrospinning through high energy and financial costs.</em></p><p><em>The composition of biocompatible polymers is used: chitosan, polyvinyl acetate (PVAC) and polyvinyl alcohol (PVA). The electrospinning method on the capillary type laboratory installation with a «bottom-up» solution is proposed for the production of nonwoven polymeric materials.</em></p><p><em>Biocompatible composite nonwovens with antiseptic properties are obtained. This is due to the fact that the proposed method of electrospinning allows to obtain nonwoven materials with a certain statistical distribution of fibers, has several features when a solution of chitosan in lactic acid is introduced into the composition. In particular, for the composition based on PVA, the proportion of fibers with a diameter of 0.5</em>–<em>0.62 μm increased by 9</em><em> </em><em>%, while for compositions based on PVAc it decreased by 21</em><em> </em><em>%. It is established that the optimal voltage of the electric field is 30 kV and the distance between the electrodes is 9</em>–<em>11 cm for the production of fibers from biocompatible PVA and PVAc with the addition of chitosan.</em></p><p><em>As a result of studies of the morphological features of the fibers obtained by optical polarization microscopy, it has been proved that with certain parameters of electrospinning, fibers with a diameter from 0.5 to 1.6 μm are obtained. As a result of determining the statistical distribution of polymer fibers in nonwoven material in diameter, it has been found that 69</em>–<em>94</em><em> </em><em>% of the fibers have a diameter of 0.5</em>–<em>0.72 μm.</em></p><p><em>A part of the fibers obtained in the laboratory installation of capillary electrospinning correspond to the area of nano-dimensions, which opens up prospects for obtaining biocompatible nanofibers with antiseptic and fungicidal properties. Therefore, the production of polymer biocompatible nonwovens by electrospinning can be used to create therapeutic systems.</em></p>
Authors and Affiliations
Olena Ishchenko, Viktoriia Plavan, Ilya Resnytskyi, Irina Liashok
Keywords
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- EP ID EP527515
- DOI 10.15587/2312-8372.2018.146471
- Views 133
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