Profile of focal liver lesions by diffusion weighted magnetic resonance imaging
Journal Title: Medpulse International Journal of Radiology - Year 2019, Vol 9, Issue 1
Abstract
Background: Focal liver disease is a common diagnostic problem referred to radiologists for evaluation owing to its nonspecific clinical presentation and marked inter-observer variation on clinical examination. Focal hepatic lesions include a large gamut of both benign and malignant lesions such as hepatic cysts, liver abscesses, haemangioma, adenoma, focal nodular hyperplasia, hepatocellular carcinoma, hepatoblastoma, metastases etc. Therefore, the determination of liver lesion count, and the nature of the lesion is important. Thus a study design for evaluation and diagnosis of focal liver lesions by diffusion weighted imaging (DWI) is conducted. Aims and Objectives: Detection and characterization of focal liver lesions, differentiation of benign from malignant liver lesions, differentiation of liver metastasis from primary liver lesions. Methods: Total 60 Patients were studied during period of October 2010 to August 2012. Diagnosis on MRI was made with background of clinical context. Final diagnosis was reached in consensus with biopsy/FNAC, wherever applicable, or clinical, laboratory, other imaging modality findings and follow up. Results: A total of 60 patients with 267 focal liver lesions were studied. Age range was of 16-95 years. Mean age was 52.75 years. Out of 60 patients 31 patients had benign lesions and 29 patients had malignant lesions. 28.33% of patients were in age group of less than 40 years. Most malignant lesions were seen in the age group of 61-70 years. Most of the HCC were seen in the age group of 61-70 years. All lesions were common in males namely HCC (66.67%), metastasis (58.82%), simple cysts (71.42) except haemangiomas and hydatid cysts which were equally seen in males and females. Out of 267 focal liver lesions in 60 patients, 101(37.83%) were benign lesions and 166(62.17%) were malignant lesions. Most common lesion was metastasis (52.8%). Maximum numbers of lesions were between 2.1-5.0cm. Average size of lesion was 3.72 ± 2.39 cm. Conclusion: Diffusion-weighted (DWI) MR imaging can be used for liver lesion detection and characterization, with better results with potential additional value to routine MRI sequences.
Authors and Affiliations
Harish K, Basavaraj N Biradar
Keywords
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