PROFILE OF HAEMOPHILIA PATIENTS IN MANIPUR
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 33
Abstract
BACKGROUND The deficiency of blood coagulation factor VIII (F-VIII) and factor IX (F-IX) are called Haemophilia A and B respectively. They are inherited as X-linked recessive traits. They are the most common hereditary haemorrhagic disorders. Patients have increased bleeding tendency especially the joints, muscles and after any trauma. The treatment for haemophilia is by providing factors VIII and IX. MATERIALS AND METHODS The aim of the study was to know various clinical manifestations of the disease in Manipur. The study was conducted in the Department of Medicine, Jawaharlal Nehru Institute of Medical Sciences, Imphal from 1st August 2017 till 31st May 2018. The study design was a descriptive study. Any patient who is diagnosed as haemophilia A or B was included in the study. Patients who had any other bleeding disorder, refused to give consent for the inclusion in the study and patients belonging to other states of India were excluded from the study. RESULTS Sixty-five patients presented with complaints of increased bleeding. Thirty-five patients were included in the analysis. Out of these 35 patients, there were 30 (85.7%) cases of Haemophilia A and 5 (14.53%) cases of Haemophilia B. There was no family history in 25 cases (71.43%). The patients in the study had presented pain and swelling in the joints in majority consisting of 19 cases (54.29). Not a single patient was in prophylaxis due to lack of adequate factors. CONCLUSION Early treatment after any bleeding episodes and prophylaxis will be essential in preventing various complications.
Authors and Affiliations
Irom Anil Singh, T. Ginzaniang, P. Vedanti Devi, A. Meina Singh, N. Dhanachand Singh, Kh. Yoihenba, Sadam Hussain
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