Profile of Multidrug Resistant Acinetobacter Baumannii Infections among Hospitalized Patients
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 6
Abstract
Background: Infections by Acinetobacter baumanniiis posing serious healthcare-associated infections [HAIs] and the incidence is increasing, with many strains now being multidrug resistant [MDR]. MDR Acinetobacter baumannii confer a high risk of morbidity and mortality to hospitalized patients. Aim: This study aimed to describe some of the common risk factors seen among hospitalized patients with Acinetobacter infection. Materials and methods: Acinetobacter baumannii isolates from invasive infection sites, numbering 120 were analysed. Clinical details and risk factors were documented in selected inpatients during the study period. Results: Multidrug resistant [MDR] strains were 87% among all the isolates. Resistant to meropenem and imipenem were 75% and 62% respectively. The major risk factors associated with acquisition of MDR A.baumannii infection among the patients were hospital stay of more than 2 weeks [74.10%], followed by stay in ICU [72.50%], presence of indwelling intravascular device[69.10 %,] and mechanical ventilation [52.50%]. Positive blood culture for A.baumannii was associated with a mortality rate of 85%, with a confidence interval of [CI=82%-88%]. Conclusion: Significant risk factors were prolonged hospital stay, intravenous devices and mechanical ventilation. Further development of A.baumannii bacteremia is associated with a high mortality rate. Therefore to constrain the infection rate, both antibiotic policies and infection control policies have to be strictly followed.
Authors and Affiliations
Anandhalakshmi Subramaniyan
Keywords
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