Profile of Testicular Germ Cell Tumors in Kashmir: A Retrospective Analysis
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2017, Vol 5, Issue 4
Abstract
Background: Testicular tumors are the most common solid neoplasm in young men. Germ cell tumors (GCT) constitute over 90% of all the malignant testicular neoplasms. The incidence of testicular tumors shows a significant geographic variation with the highest number of cases being reported in Scandinavia, Germany and Switzerland and lowest in Asian and African nations. Presently, there are only a few well-established risk factors for this disease, notably cryptorchidism and age. However, for the most part, the etiology of testicular cancer remains unknown. Aim and Objective: To analyze the profile of testicular GCT at a tertiary cancer center in Kashmir. Materials and Methods: This retrospective analysis of testicular germ cell tumor cases was performed in the year 2017 on 40 patients enrolled in the Department of Radiation Oncology, Government Medical College, Srinagar, from 2012 to 2017. Results: Of the 40 patients analyzed, majority had seminomatous histology. Most of them presented with unilateral disease with laterality toward the right side. Bilateral tumors presented at an earlier age than unilateral disease. Most of the patients enrolled belonged to rural areas. Tumor markers such as lactate dehydrogenase and beta-human chorionic gonadotropin had statistically significant association with the overall stage of disease.
Authors and Affiliations
Syed Arshad Mustafa, Vinod Mitla, Saqib Zaffar Banday, Sanaullah Kuchay
Keywords
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