Prognostic factors in colorectal cancers
Journal Title: Dicle Tıp Dergisi - Year 2014, Vol 41, Issue 4
Abstract
Objective: The aim of this study is to investigate retrospectively the impact of the various prognostic factors on survival in patients with colorectal cancer. Methods: The clinical records, pathology and operation reports of 126 patients in 154 patients operated for colorectal cancer General Surgery Clinic of Fırat University Hospital between 1994 and 2005 years. The effects of the prognostic factors on 2-years, 5-years and 10-years survival, overall survival (OS) and disease-free survival (DFS) were evaluated. The survival durations are presented as months. Results: The mean age was 57.5 ± 15.2. The median duration of follow-up was 44,5 month. The median OS was 60 months. The median DFS in stage I-III patients was 62 months. According to the univariate analysis, the factors found significant in both OS and DFS rates were the following; stage of the cancer, extent of bowel wall penetration, lymph nodes metastasis, distant metastasis, pathologic stage, surgical margin, pretreatment CEA levels and type of surgery. The age and histologic type of tumor were related to only OS. The following variables were independent prognostic factors for both OS and DFS as determined by multivariate analysis; stage of the cancer, extent of bowel wall penetration and distant metastasis. Conclusion: A large number of prognostic factors are available to help predict the outcome of patients with colorectal cancer after surgery. In order to predict survival more accurately, a scoring system can be created that involving not only prognostic factors determined by multivariate analysis, but also prognostic factors determined by univariate analysis. Key words: Colorectal cancer, survival, prognostic factor
Authors and Affiliations
Ahmet Türkoğlu, Ziya Çetinkaya, Mustafa Girgin, Refik Ayten, Burhan Kanat, Kenan Binnetoğlu, Ali Aksu
Keywords
Related Articles
- EP ID EP89090
- DOI 10.5798/diclemedj.0921.2014.04.0507
- Views 132
- Downloads 0
The effects of intravenous aminoacid infusion on myocardial functions and postoperative analgesia during abdominal aortic surgery
Objective: Effects of intravenous aminoacid infusion on myocardial functions and postoperative analgesia in abdominal aortic surgery were investigated. Materials and methods: Forty patients were randomly divided into...
Osteogenesis imperfektalı yetişkin hastada zoledronik asit tedavisi: Bir olgu ve literatür derlemesi
Osteogenesis İmperfecta (Oİ) düşük kemik kütlesi ve kemik kırılganlığı ile karakterize nadir görülen kalıtsal bir hastalıktır. Temel patoloji tip-1 kollajen biyosentezinin bozukluğu sonucunda kollajenin kusurlu ve eksik...
Proksimal hipospadyaslı olgularda TIP üretroplasti sonuçları
Amaç: Proksimal hipospadyaslı primer vakalarda uygulanan “tubularized incised plate” üretroplasti (TIPU) tekniğinin klinik sonuçlarının değerlendirilmesini amaçladık. Yöntemler: Kliniğimizde 2003–2011 tarihleri arasınd...
Rize bölgesinde yaşayan gebe kadınlarda HBsAg, AntiHBs ve Anti-HCV seroprevalansı
Amaç: Rize bölgesinde yaşayan gebe kadınlarda HBsAg, AntiHBs ve Anti-HCV seroprevalansının belirlenmesi. Yöntemler: Bu retrospektif çalışmaya, 2008-2012 yılları arasında Recep Tayyip Erdoğan Üniversitesi Tıp Fa...
A Rare Complication after Caudal Epidural Steroid Injection: Persistent Hiccup
Lumbar caudal epidural steroid injection (LKES ) is one of the non-surgical treatment of back pain. In this case report; we presented persistent hiccup after lomber caudal epidural steroid injection for chronic lo...