Prognostic factors in Guillain-Barre syndrome

Journal Title: Dicle Tıp Dergisi - Year 2014, Vol 41, Issue 4

Abstract

Objective: Guillain–Barre syndrome (GBS) is an immune-mediated disorder of peripheral nerves resulting as acute inflammatory demyelinating polyradiculoneuropathy. GBS has a heterogeneous clinical course and laboratory findings. Acute onset and progressive course, and is usually associated with a good prognosis but some forms have a poor prognosis. Factors that can affect the prognosis of GBS have been investigated in several studies. Assessment of poor prognostic factors of GBS plays a vital role in the management and monitorization of patients. Methods: In this retrospective study of patients admitted to the acute phase of GBS removing clinical and laboratory profiles and was planned to investigate the prognostic factors. Results: Totally 23 patients (Female/male: 16/7) were recruited. Mean age was 47 (range: 17-70) years. Statistically significant poor prognostic factors were advanced age (p=0.042), erythrocyte sedimentation rate (p=0.027) and serum albumin level (p=0.007). Conclusion: Advanced age, increased ESR and decreased albumin levels were found as poor prognostic factors in GBS. Key words: Guillain-Barre syndrome, advanced age, sedimentation, albumin

Authors and Affiliations

Semra Mungan, Esra Eruyar, Işıl Güzel, Şule Bilen, Fikri Ak

Keywords

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  • EP ID EP100154
  • DOI 10.5798/diclemedj.0921.2014.04.0496
  • Views 147
  • Downloads 0

How To Cite

Semra Mungan, Esra Eruyar, Işıl Güzel, Şule Bilen, Fikri Ak (2014). Prognostic factors in Guillain-Barre syndrome. Dicle Tıp Dergisi, 41(4), 667-670. https://europub.co.uk/articles/-A-100154