Prognostic Implication of Serum Magnesium Levels in Patients with Chronic Stable Asthma
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 5
Abstract
Background: Magnesium has been used in the treatment of acute exacerbation of asthma for a long time, but the role of hypomagnesaemia in chronic stable asthma and its prognostic implications have not been fully established. Objectives:We conducted this study – (i)To assess the levels of serum magnesium and its prognostic implications in patients with chronic stable asthma and (ii) to find out any correlation between the severity of asthma and hypomagnesemia. Setting: Government Rajaji hospital ,Madurai, TamilNadu. Period of study: June 2013 to November 2013 Study Design: 100 patients with chronic stable asthma attending outpatient departments of Thoracic Medicine and General Medicine and 50 healthy controls were randomly selected. The asthmatic patients were assessed by spirometry and serum magnesium levels were determined for all . Descriptive statistics were applied to the obtained data and results were analyzed as significant if the p value was <0.05. Results: 34 percent of asthmatic patients were found to have hypomagnesemia. The mean levels of magnesium was 1.55 in cases and 2.03 in controls (p < 0.001). Conclusion: There was statistically significant hypomagnesemia in patients with chronic stable asthma. Low levels of magnesium were found to correlate with severity of asthma and. There was no significant correlation of magnesium levels with age, gender or duration of asthma.
Authors and Affiliations
Dr. S. Sopnajothi Md, dr. Sooriyakumar Md, Prof. Dr. S. Vadivelmurugan Md, Prof. Dr. T. Ravikumar Md, Prof. Dr. Purusothaman Md
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