Prognostic Profile of Scrub Typhus in Association with Co Existing Clinical Infection in Hadoti Region of Rajasthan
Journal Title: International Journal of Medical Science And Advanced Clinical Research (IJMACR) - Year 2019, Vol 2, Issue 2
Abstract
Scrub typhus is a disease caused due to infection with Orientia tsutsugamushi, and is spread by leptotrombidiummites (chiggers). In tropical areas, concurrent infectionof malaria and dengue can occur as both are transmitted by mosquito. But the mode of transmission of scrub typhusis exclusive in terms of a vector insect, a bite by chigger larvae, and therefore has no connection with other mosquito-borne or air-borne or water-borne infections. Henceforth concomitant O.tsutsugamushi with other parasite or chronic infection in an individual is infrequent.We retrospectively studied clinically suspected and serologically confirmed cases of scrub typhus presented at medicine department of tertiary health care hospital at Kota. The cases were divided into two groups: 1. Group A - Comprising of patients diagnosed with scrub typhusonly and 2. Group B- Patients diagnosed with scrub typhus and any other parasitic (malaria), viral (dengue, HBS, HSV) or other bacterial (tuberculosis) infection. The clinical data and outcome of the two groups were compared and statistically analyzed.A total of 37 scrub typhuscases were included and during the study, concomitant another infection was noted among 18 (48.65%) of cases. These were Dengue virus (27.03%), Plasmodiumvivax(18.92%), Plasmodiumfalciparum (8.11%), Mycobacterium tuberculosis(2.70%), Herpes simplex virus (2.70%) and Hepatitis B virus (2.70%). In this study, the most common complications included thrombocytopenia (75.68%), anaemia (48.65%), urinary tract infection (45.95%), abnormal respiratory system findings (40.54%), encephalitis (27.03%) and splenomegaly (24.32%). The comparison of groups showed that patients with coinfection presented with more severe deranged laboratory reports; severe complications involving CNS, respiratory system and the urinary system.Thus, concomitant infection in a patient of scrub typhus is not infrequent and treating physicians should keep this in mind while making a diagnosis,hence ones a diagnosis of scrub typhus has been made,relevant concomitant intection like dengue,malaria etc should also be taken into account as they influence the prognosis gravely.
Authors and Affiliations
Rahul Chandel
Keywords
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