Prognostic Value of Cortisol in Patients with Acute Ischemic Stroke
Journal Title: Zahedan Journal of Research in Medical Sciences - Year 2017, Vol 19, Issue 2
Abstract
Background: Activation of the hypothalamo-pituitary-adrenal axis has been shown in acute ischemic stroke. Some recent studies suggest that serum cortisol level may have prognostic value in patients with ischemic stroke. The aim of this study was to evaluate the prognostic value of cortisol in patients with acute ischemic stroke. Methods: In this prospective observational study, 51 patients with acute ischemic stroke were evaluated. Cardioembolic and lacunar strokes were excluded. In the first 24 hours of admission, serum cortisol level, national institutes of health stroke scale (NIHSS), diabetes and hypertension were assessed to determine their value to predict mortality within 90 days. The results were analyzed using descriptive statistics, t-test, chi-square test and logistic regression. Results: In this study, 26 patients (51%) were female and the rest were male. Serum cortisol level was normal in 37 patients (72.5%). 14 patients died (27.5%) during the follow-up period. The mean serum cortisol level of dead patients were 33.48 ± 15.14 μg/dL and for alive patients was 35.10 ± 19.74. This difference was not statistically significant. After statistical analysis using logistic regression, no significant correlation between serum cortisol level and mortality was seen. Conclusions: Although ischemic stroke is associated with change in serum cortisol level but this change has no prognostic value.
Authors and Affiliations
Farhad Iranmanesh, Behnaz Sedighi, Bentolhoda Ziaadini
Keywords
Related Articles
- EP ID EP307200
- DOI 10.5812/zjrms.6187
- Views 106
- Downloads 0
Which Health Literacy Skills Are Associated with Smoking?
null
Antibiotic Resistance and Carriage Integron Classes in Clinical Isolates of Acinetobacter Baumannii from Isfahan Hospitals, Iran
Background: Acinetobacter baumannii is a significant nosocomial pathogen around the world, especially in the intensive care unit that most A. baumannii infections are caused by the outbreak strains. Objectives: This stu...
Antibiotic resistance of Neisseria gonorrhoeae isolated from gonorrhoeae patients
Background: The objective of this study was to determine antibiotic susceptibility and penicillinase production by Neisseria gonorrhoeae strains isolated from gonorrhoeae patients in Zahedan. Materials and methods: In a...
The Relationship between Impulsive and Reflective Problem Solving Behavior
Background: Problem solving is an axial ability of educational promotion. Impulsive individual against reflectivity has fewer tendencies to involve in solving different problems. The purpose of present study was to eva...
The effect of two nutritional methods in changes of anthropometric indexes in obese parents and their children
Background: Parents obesity has a direct relation with their children obesity. The aim of this study is to determine the effect of two methods of weight loss in obese parents and their children. Materials and Method: W...