Prognostic Value of Cortisol in Patients with Acute Ischemic Stroke
Journal Title: Zahedan Journal of Research in Medical Sciences - Year 2017, Vol 19, Issue 2
Abstract
Background: Activation of the hypothalamo-pituitary-adrenal axis has been shown in acute ischemic stroke. Some recent studies suggest that serum cortisol level may have prognostic value in patients with ischemic stroke. The aim of this study was to evaluate the prognostic value of cortisol in patients with acute ischemic stroke. Methods: In this prospective observational study, 51 patients with acute ischemic stroke were evaluated. Cardioembolic and lacunar strokes were excluded. In the first 24 hours of admission, serum cortisol level, national institutes of health stroke scale (NIHSS), diabetes and hypertension were assessed to determine their value to predict mortality within 90 days. The results were analyzed using descriptive statistics, t-test, chi-square test and logistic regression. Results: In this study, 26 patients (51%) were female and the rest were male. Serum cortisol level was normal in 37 patients (72.5%). 14 patients died (27.5%) during the follow-up period. The mean serum cortisol level of dead patients were 33.48 ± 15.14 μg/dL and for alive patients was 35.10 ± 19.74. This difference was not statistically significant. After statistical analysis using logistic regression, no significant correlation between serum cortisol level and mortality was seen. Conclusions: Although ischemic stroke is associated with change in serum cortisol level but this change has no prognostic value.
Authors and Affiliations
Farhad Iranmanesh, Behnaz Sedighi, Bentolhoda Ziaadini
Keywords
Related Articles
- EP ID EP307200
- DOI 10.5812/zjrms.6187
- Views 102
- Downloads 0
Efficacy of Dialectical Behavior Therapy on Stress, Resilience and Coping Strategies in Irritable Bowel Syndrome Patients
Background: Irritable bowel syndrome (IBS) is the most common gastrointestinal disorder that have considerable psychological features. Objectives: This research aimed to determine the efficacy of dialectical behavioral...
Antibiotic Resistance and Carriage Integron Classes in Clinical Isolates of Acinetobacter Baumannii from Isfahan Hospitals, Iran
Background: Acinetobacter baumannii is a significant nosocomial pathogen around the world, especially in the intensive care unit that most A. baumannii infections are caused by the outbreak strains. Objectives: This stu...
Prevalence of asthma symptoms and allergic diseases with ISSAC method in children, Shiraz 2009
Background: Asthma is the most important chronic disease in children and the most common cause of school absenteeism. Its prevalence has been raised due to increased environmental and industrial. This study were designed...
Antibiotic resistance of Neisseria gonorrhoeae isolated from gonorrhoeae patients
Background: The objective of this study was to determine antibiotic susceptibility and penicillinase production by Neisseria gonorrhoeae strains isolated from gonorrhoeae patients in Zahedan. Materials and methods: In a...
Compare the Quality of Life in Type 2 Diabetic Patients with Healthy Individuals (Application of WHOQOL-BREF)
Background: Diabetes is a chronic disease that its prevalence will double in the world by 2030. According to the report of world health organization (WHO) in 2014, diabetes is the fourth main disease contributing to prem...