Prognostic value of inflammatory markers in acute coronary syndrome in a population with premature cardiovascular disease
Journal Title: Journal of Rare Cardiovascular Diseases - Year 2019, Vol 4, Issue 2
Abstract
Introduction: Inflammation plays a significant role in the development of atherosclerosis, and inflammatory markers could be used in risk assessment of patients with ischaemic heart disease. The use of such markers could be beneficial in younger patients, since in this group, prevention is more effective than treatment of myocardial infarctions, as long‐term prognoses are often unfavourable. Aim: Our goal was to examine the value of inflammatory biomarkers as an assessment tool for cardiovascular risk in a population with a premature ischaemic heart disease. Materials and Methods: We analysed laboratory test results of 100 consecutive patients hospitalized in the John Paul II Hospital in Krakow, Poland between 2014–2017. Inclusion criteria was cardiovascular disease diagnosed in coronarography under the age of 55 years for women and 45 years for men. We excluded patients with incomplete data and acute infections. The remaining 90 patients were divided into groups based on the reason of admission (myocardial infarction or elective diagnostics). Results: White blood cell count (median of 6.990 × 10 3 per/μl in comparison to 8.535 × 10 3 /μl) and absolute neutrophil count (median of 4060 × 10 3 /μl and 5360 × 10 3 /μl ) were lower in the group admitted for diagnostics. Although inflammatory biomarkers (platelet distribution width, white blood cells) were within normal ranges, we observed higher values (above the medians for studied population) in the group admitted to hospital due to acute coronary syndrome. Conclusion: Inflammatory biomarkers could be useful in the assessment of cardiovascular risk in patients with a premature ischaemic heart disease. Since the measured values of the inflammatory biomarkers were within normal range in the examined population, further studies should be conducted to determine appropriate cut‐off values. JRCD 2019; 4 (2): 37–41.
Authors and Affiliations
Agnieszka Pura, Marta Wilk, Maria Olszowska
Keywords
Related Articles
- EP ID EP629831
- DOI 10.2041/jrcd.vol4no2.373
- Views 81
- Downloads 0
Ablation of incessant supraventricular tachycardia in pregnancy (RCD code: VIII-V-3A.O)
We present a case of a 40‑year‑old woman, 4‑months pregnant (in vitro fertilization), admitted to a hospital due to incessant supraventricular tachycardia with a rate of 187 beats/min. Attempts to stop the arrhythmia (3...
Primary hyperaldosteronism presenting as recurrent polymorphic ventricular tachycardia
Primary hyperaldosteronism (PH) is a frequently overlooked cause of secondary hypertension mostly due to an aldosterone‐producing adrenal adenoma. We report the case of a 48‐year‐old female who presented with recurrent e...
“Let (the hospital) serve!”. Pope John Paul II. Visit at the John Paul II Hospital in Krakow, 9 June 1997
This June, here in Krakow we witness two important anniversaries. First, our hospital, now called after Pope John Paul II, is already 100 years old. Secondly, 20 years have already passed since the visit on the hospital’...
Journal of Rare Cardiovascular Diseases: Moving towards maturity, and implementing the Krakow RCD Classification as a milestone
Dear Readers – our Friends and Colleagues,The present, third, issues of your quarterly Journal of Rare Cardiovascular Diseases is an important landmark in the life of the Journal; the life that presents a process from in...
Coronary sinus atrial septal defect in adult (RCD code: IV‑2B.1)
We present a case report of a 45‑year old man, who was admitted to medical center due to dyspnea and cough. Right bundle branch block was detected on electrocardiography. Transthoracic echocardiography demonstrated coron...