Progress in clinical application of esketamine in pediatric anesthesia
Journal Title: Chinese Journal of Clinical Research - Year 2024, Vol 37, Issue 4
Abstract
Ketamine is a commonly used anesthetic drug, but its clinical use declined in the late 1990s due to its postoperative nightmares, extrapyramidal syndrome, and a tendency to abuse. As an isomer of ketamine, esketamine is applied in a smaller dose than racemic ketamine, with strong analgesic and sedative effects, fewer cardiovascular and psychiatric adverse reactions. It has a significant application value in pediatric anesthesia with fast metabolism and high clearance rate invivo, slight impact on childrens respiratory and circulation, and rapid awakening and recovery.
Authors and Affiliations
WANG Lu*, YAN Wenjun
Keywords
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- EP ID EP734601
- DOI 10.13429/j.cnki.cjcr.2024.04.004
- Views 5
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