PROLACTIN LEVELS BEFORE AND AFTER ELECTROCONVULSIVE THERAPY AND ITS CORELATION WITH CLINICAL IMPROVEMENT IN PSYCHOPATHALOGY
Journal Title: GJRA-Global Journal For Research Analysis - Year 2018, Vol 7, Issue 7
Abstract
BACKGROUND: It is a well-known fact that prolactin increases after Electroconvulsive Therapy (ECT), but in later studies it was found that the amount of prolactin rise after each ECT gradually declines on successive ECT. Many studies have found that there is a correlation between this prolactin drop and improvement in psychopathology. But the results found were inconsistent and only limited to depression. AIM: To see the serum prolactin changes during a course of ECT in patients suffering from BPAD mania and to assess whether any correlation exists between these changes and improvement in psychopathology. METHORD: 20 inpatients meeting diagnostic criteria for BPAD mania as per ICD-10 who were planned to receive ECT were taken as cases and 20 BPAD mania patients not receiving ECT were taken as controls. Blood for prolactin and psychopathology on YMRS assessed three times in each case. First at baseline, second after 1st ECT and third after last ECT. Similarly controls were assessed at baseline and after three weeks for prolactin and psychopathology. RESULTS: In patients who received ECT, serum prolactin levels were significantly raised after 1st ECT (mean 78.65) compared to baseline (mean 54.02). Prolactin level significantly decreased after a course of ECT (mean 67.22). There was no significant correlation between prolactin changes and in YMRS score. CONCLUSION: There is no significant correlation between prolactin changes during a course of ECT and improvement in psychopathology in BPAD mania patients suggesting the prolactin rise may be an epiphenomenon to ECT rather than reflection of therapeutic process.
Authors and Affiliations
Dr. Shalini Bijali, Dr D. Ram, Dr. S. K. Munda, Dr. Vikalp Wasnik
Keywords
Related Articles
- EP ID EP457844
- DOI -
- Views 80
- Downloads 0
TO STUDY THE OPINION OF LOCAL NGO, S REPRESENTATIVE IN AMALNER ABOUT SOCIAL WORK EDUCATION
“To study the opinion of local NGO, s in Amalner about social work Education” researcher study the opinion of NGO, s through interview schedule to know the social work education. Social work is an academic discipline and...
ORGANIC FARMING – PROBLEMS AND PROSPECTS
The organic farming sector is suffering from a lot of problems such as insignificant growth. Organic Farmers find it difficult to continue their organic farming practices due to various reasons like inadequate support fr...
EFFECT OF SLEEP QUALITY ON COGNITION AND VISUAL REACTION TIME
Introduction: Sleep duration and quality is affected in college students because of educational and social factors. This affects their learning, behavior, performance and development. Methodology: This study was aimed to...
CONNECTIVITY CHALLENGES OF NORTH EASTERN REGION OF INDIA AND ITS ACT EAST POLICY
India embarked with its Look East Policy(LEP), that later evolved as Act East Policy (AEP) with multifaceted strategic ambition. It had two major perspectives, namely Security and Economy. India also sees its North East...
CORRELATION ON ENVIRONMENT FACTORS, LEARNING HABITS AND SELF-ESTEEM OF HIGHER SECONDARY MATHEMATICS STUDENTS
It is an attempt to determine the signicant relationship between environmental factor, learning habits and Self-esteem at higher secondary mathematics students with reference to certain demographic variable such as gend...