Prophylactic bundle for radiation-induced oral mucositis in oral or oropharyngeal cancer patients
Journal Title: Journal of Cancer Research & Therapy - Year 2014, Vol 2, Issue 1
Abstract
Objective: In order to prevent and treat radiation-induced adverse events, especially oral mucositis, in patients with oral or oropharyngeal cancer receiving radiotherapy or chemoradiotherapy, a prophylactic bundle, i.e., a set of oral care management procedures, is conducted and assessed. Subjects and methods: The subjects were 30 patients with squamous cell carcinoma of the oral cavity or oropharynx who underwent radiotherapy. The patients received the prophylactic bundle to prevent radiation-induced oral mucositis during radiotherapy. Results: Severe oral mucositis, grade 3, was observed in 5 of 30 patients (17%). The occurrence of oral mucositis was lower than in previous reports. The prophylactic bundle included the use of spacers, administration of pilocarpine hydrochloride, appropriate oral care, and use of steroid ointment during radiotherapy. Conclusions: This preliminary study suggests that the prophylactic bundle, when performed in oral or oropharyngeal cancer patients, decreases severe radiation-induced oral mucositis. Further evaluation is needed in multi-centre, prospective, randomized trials.
Authors and Affiliations
Kawashita Y, Hayashida S, Funahara M, Umeda M, Saito T
Keywords
Related Articles
- EP ID EP547280
- DOI 10.14312/2052-4994.2014-2
- Views 55
- Downloads 0
O-acetylated gangliosides: Structure, biosynthesis, immunogenicity, functions and their potential for cancer immunotherapy
Sialic acid O-acetylation is a developmentally regulated modification of gangliosides implicated in ontogeny and tumor progression. Their existence has been underestimated in the past because of their alkali-labile natur...
Cancer estimation of incidence and survival in Algeria 2014
Cancer is one of the major public health problems in Algeria. In the last 25 years, a significant increase in the incidence of the major types of cancers has been observed in both sexes. Moreover, the 5-year survival rat...
How health system factors influence referral decisions in patients that may have cancer: European symposium report
Objective: To identify the system and other non-clinical factors that may influence a General Practitioners’ decision on whether to refer a patient who may have cancer. Study design: Expert group discussion and consensus...
Outcomes of social support programs in brain cancer survivors in an Australian community cohort: a prospective study
This study evaluated the impact of social support programs on improving cancer related disability, neuro-cognitive dysfunction and enhancing participation (quality of life (QoL), social reintegration) in brain tumour (BT...
30 years of preventive studies of uterine cervical cancer 1982-2012
Purpose: To show and describe the clinical evolution of cervical cancer screening patients following the protocol established by the University of Padua. Methods: 12,679 patients were examined using Pap smear, colposcopy...