Protective role of black tea and vitamin C during sub-acute toxicity of carbofuran in rats
Journal Title: Progress in Health Sciences - Year 2016, Vol 6, Issue 2
Abstract
Purpose: Carbofuran toxicity on rats was studied during sub-acute exposure. This work was undertaken to evaluate the protective effect of aqueous black tea extract and vitamin C against a rat model of oxidative stress induced by treatment with carbofuran, an organocarbamate insecticide. Materials and methods: The levels of lipid peroxidation, reduced glutathione and ascorbic acid were assessed by determining the extent of oxidative stress in the erythrocytes of rats. Results: The results clearly demonstrated that the treatment of rats with sub-acute concentration of carbofuran caused significant elevation in the levels of oxidative stress and decrease in the contents of glutathione and ascorbic acid. The introduction of black tea extract and vitamin C augmented the antioxidant defense mechanism in alleviating the carbofuran induced oxidative stress. Conclusion: The findings that the pretreatment with black tea and vitamin C can mitigate carbofuran induced toxicity lend evidence that supplementation with either black tea extract and/or vitamin C have a therapeutic potential in amelioration of oxidative stress in mammalian systems
Authors and Affiliations
D. Kumar, B. Sharma, SI Rizvi
Keywords
Related Articles
- EP ID EP186964
- DOI 10.5604/01.3001.0009.5162
- Views 64
- Downloads 0
The extent and manner of passing the information concerning the surgical implantation of cells, tissues or organs to the recipient of the transplant under the Polish law
The purpose of article is to present, analyse and evaluate the effective legal regulations concerning the extent and manner of passing information about surgical implantation of cells, tissues or an organ to the recipie...
Role of quality in healthcare service provision process
Introduction: The role of quality in achieving, improving, maintaining repeatable processes, service level guarantee patient satisfaction, determinants of hospitals.Objective:Identification of the mechanisms consistent...
Cardio-respiratory status of stone grinders and brick field workers from west Bengal, India
Introduction: Quartz crushing and brick making industry are informal and demands heavy manual labour. They are socio-economically backward and are unable to avail of social security’s scheme meant for protection of...
Patients and nurses attitude towards pain management with alternative methods
Introduction: Alternative therapeutic methods are used frequently by health care professionals for pain management, particularly for patients whose disease is in advanced stage. Purpose: To assess attitudes toward alter...
Effect of a medicinal agent, possessing antioxidant and antihypoxant properties, on the state of oxygen homeostasis and lipid peroxidation under experimental pneumoconiosis in albino rats
Introduction: Pneumoconioses (Pc) are interstitial pulmonary diseases of professional genesis, caused by long-term inhalation of high dust concentrations. Pcafflict 26.6-53% of the workers, exposed to dust contamination....