Proteinuria in a Child with Bilateral Vesicoureteral Reflux and Dysplastic Kidneys
Journal Title: Macedonian Journal of Medical Sciences (MJMS) - Year 2009, Vol 2, Issue 4
Abstract
Vesicoureteral reflux associated with congenital dysplastic kidneys is the still an important etiological factor in children with chronic renal failure. Proteinuria in a child with reflux and scarring is an unfavorable prognostic parameter preceding the functional renal deterioration. Although there are no controlled studies in children angiotensin converting enzyme inhibitors have been used in those with proteinuria or hypertension to slow down progression of the disease. Herein we present a female child with bilateral reflux and significant proteinuria. Stress tolerance test and analysis of urinary proteins with SDS-PAG electrophoresis disclosed typical orthostatic proteinuria. Therefore children with reflux and congenital/ acquired scarring should have regular quantitative and qualitative evaluation of proteinuria to avoid unnecessary treatment in those with typical orthostatic pattern.
Authors and Affiliations
Nadica Ristoska Bojkovska| University Children’s Hospital, Faculty of Medicine, University “Ss Kiril and Metodij”, Skopje, Republic of Macedonia, Vladimir Lozanovski| Medizinische HochSchule, Hannover, Germany, Petraki Korneti| Department of Medical and Experimental Biochemistry, Faculty of Medicine, University “Ss Kiril and Metodij”, Skopje, Republic of Macedonia, Velibor Tasic| University Children’s Hospital, Faculty of Medicine, University “Ss Kiril and Metodij”, Skopje, Republic of Macedonia
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- EP ID EP8718
- DOI 10.3889/MJMS.1857-5773.2009.0067
- Views 390
- Downloads 19
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