Psychotic symptoms and cognitive impairment in neurosarcoidosis. Case report and review of literature
Journal Title: Psychiatria Polska - Year 2012, Vol 46, Issue 6
Abstract
Clinical involvement of the nervous system occurs in about 5% of patients with sarcoidosis. We describe a fatal case of a young patient with neurosarcoidosis with a relatively rare psychotic syndrome in the course of neurosarcoidosis, presenting itself as a depressive syndrome with delusions. The neurological manifestations consisted of cerebellar symptoms, peripheral neuropathy and general epileptic seizures. Cerebrospinal fluid examination, serum angiotensin-converting enzyme level, magnetic resonance imaging, chest radiography, gallium isotope scanning and other tests were used as diagnostic tools. He was treated with steroids, methotrexate and neuroleptics ineffectively. The patient died because of complications related to neurosarcoidosis. The diagnosis of neurosarcoidosis was confirmed by autopsy.
Authors and Affiliations
Małgorzata Gaweł, Izabela Domitrz, Dorota Dziewulska, Andrzej Dąbrowski, Witold Przyjałkowski, Marek Gołębiowski, Hubert Kwieciński
Keywords
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