Pulmonary Aspergillosis Mimicking Primary Lung Cancer
Journal Title: Pulmonary Research and Respiratory Medicine – Open Journal - Year 2013, Vol 2, Issue 2
Abstract
A 68-year-old man was transferred to our hospital because of abnormal lung nodule. He was a social drinker and a current smoker with a history of 70 pack-years. He had no symptoms and was a good nutritional status. Based on the pulmonary function tests, he was diagnosed with chronic obstructive lung disease stage II by Global Initiative on Obstructive Lung Disease staging system. Thoracic Computed Tomography (CT) showed the irregular-shaped nodule measuring 15 mm in size with spiculation at right S1 (Figure A), which accompanied by emphysematous lung changes. On thoracic FDG PET/CT, the nodule demonstrated the intense standardized uptake values both in the early (max 3.4) and delayed (max 4.2) phases, suggesting malignancy (Figure B). However, video-assisted thoracic surgery biopsied specimens on Hematoxylin and eosin stains showed that the nodule was consisted of central necrotic component surrounded by microabscesses and fibrotic granulomatous tissues (Figure C) in which contained filamentous fungi on Grocott’s methenamine silver stain (Figure D) with calcium oxalate crystal deposition, indicating of pulmonary aspergillosis. Pulmonary aspergillosis mimicking cancer was an extremely rare event,1-2 but should be included in the differential diagnosis for solitary pulmonary nodule.
Authors and Affiliations
Takeshi Saraya
Keywords
Related Articles
- EP ID EP550084
- DOI 10.17140/PRRMOJ-2-111
- Views 111
- Downloads 0
Significance of Combined Emphysema in Idiopathic Pulmonary Fibrosis and Serum Surfactant Protein-D as a Prognostic Factor
Background and Objectives Idiopathic pulmonary fibrosis (IPF) is a chronic disease of unknown aetiology and is often associated with a syndrome called combined pulmonary fibrosis and emphysema (CPFE). This study aimed to...
Pulmonary Complications in Patients with Brain Injury
Critically ill patients with brain injury associated with organ dysfunction among which include pulmonary involvement as a determinant of morbidity and mortality. The aim of this paper is to review the major complication...
A Review of Non-Pharmacological Pulmonary Rehabilitation for Patients Receiving Palliative Care
Introduction: Dyspnea is common in patients experiencing chronic and malignant lung conditions. It is a very distressing symptom that often results in anxiety and depression. Pulmonary rehabilitation together with pallia...
Diaphragm Ultrasonography as a Tool To Assess the Respiratory Issues of a Patient With Amyotrophic Lateral Sclerosis (ALS)
A 73-year-old woman with Amyotrophic Lateral Sclerosis (ALS) presented at a universityaffiliated community hospital with increasing shortness of breath. She was diagnosed with ALS 2 years prior to this event, and she had...
Diagnosis and Management of Spontaneous Pneumothorax in the Emergency Department: A Review of the Most Current Clinical Evidence for Diagnosis and Treatment
Background Spontaneous non-traumatic pneumothorax is a relatively common clinical presentation in the Emergency Department. The diagnosis of spontaneous non-traumatic pneumothorax has evolved from basic chest radiography...