Pulmonary function test and HRCT findings in patients with systemic lupus erythematosus
Journal Title: MedPulse -International Medical Journal - Year 2017, Vol 4, Issue 2
Abstract
Objectives: To study the findings of Pulmonary function test and HRCT in patients with systemic lupus erythematosus. Materials and Method: The patients attending outpatient departments or admitted to wards during the period, who fulfilled the revised ACR criteria for classification of SLE were included in the study. Detailed medical history including age, sex, age of onset, duration of illness and various clinical presentations especially pulmonary manifestations (e.g. cough, chest pain, dyspnea and cyanosis) was recorded in a preformed proforma. Thorough clinical examination with special attention to chest examination was performed in all the study patients. Plain X-ray chest and HRCT was performed in all the patients. Pulmonary function tests also performed in all the patients and the findings observed were recorded. Results: Majority of the patients were in the age group of 15-30 years of age (48%) followed by 31-45 years of age (44%). The female to male ratio was 7.33:1. Symptom of pulmonary manifestations were seen in 28% patients. Pulmonary function test with decreased diffusion lung capacity was positive in 68% patients. HRCT was found to have interstitial lung pattern in 72% patients. The sensitivity of PFT 94.44% and specificity of 100% in diagnosing the pulmonary manifestation. The two-sided P value is < 0.0001, considered extremely significant. Conclusion: PFT and HRCT showed pulmonary manifestations positive in 68% and 72% patients. The sensitivity of PFT in diagnosing the pulmonary manifestation was 94.44% with specificity of 100%. Thus PFT can be used as effective tool in diagnosing asymptomatic pulmonary manifestation as HRCT.
Authors and Affiliations
Manohar Joshi, Manish Pendse
Keywords
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