Pulmonary function test and HRCT findings in patients with systemic lupus erythematosus
Journal Title: MedPulse -International Medical Journal - Year 2017, Vol 4, Issue 2
Abstract
Objectives: To study the findings of Pulmonary function test and HRCT in patients with systemic lupus erythematosus. Materials and Method: The patients attending outpatient departments or admitted to wards during the period, who fulfilled the revised ACR criteria for classification of SLE were included in the study. Detailed medical history including age, sex, age of onset, duration of illness and various clinical presentations especially pulmonary manifestations (e.g. cough, chest pain, dyspnea and cyanosis) was recorded in a preformed proforma. Thorough clinical examination with special attention to chest examination was performed in all the study patients. Plain X-ray chest and HRCT was performed in all the patients. Pulmonary function tests also performed in all the patients and the findings observed were recorded. Results: Majority of the patients were in the age group of 15-30 years of age (48%) followed by 31-45 years of age (44%). The female to male ratio was 7.33:1. Symptom of pulmonary manifestations were seen in 28% patients. Pulmonary function test with decreased diffusion lung capacity was positive in 68% patients. HRCT was found to have interstitial lung pattern in 72% patients. The sensitivity of PFT 94.44% and specificity of 100% in diagnosing the pulmonary manifestation. The two-sided P value is < 0.0001, considered extremely significant. Conclusion: PFT and HRCT showed pulmonary manifestations positive in 68% and 72% patients. The sensitivity of PFT in diagnosing the pulmonary manifestation was 94.44% with specificity of 100%. Thus PFT can be used as effective tool in diagnosing asymptomatic pulmonary manifestation as HRCT.
Authors and Affiliations
Manohar Joshi, Manish Pendse
Keywords
Related Articles
- EP ID EP176321
- DOI -
- Views 106
- Downloads 0
A Clinical Study on Serum Calcium levels and Bone Mineral Density in Pre and Postmenopausal Indian Women
Abstract: Objective: To study the correlation between serum Calcium and bone mineral density (BMD) in pre and postmenopausal women. Material and methods: The present study was a cross-sectional study. 40 women from each...
Anterior mediastinal mass: A case report of thymoma with Myasthenia gravis
Introduction: Approximately 10-12 % of patients with myasthenia gravis are found to have a thymoma, and 20-20% percent of patients with thymoma may have myasthenia gravis. Thymomatous myasthenia gravis tends to have a di...
A study of the benefits and complications after ORIF (open reduction and internal fixation) with proximal humerus locking plate in fracture proximal humerus
Background: The major goal in the treatment of the proximal humerus fracture is to promote a pain free, mobile, and stable functional shoulder joint. ORIF can offer excellent outcomes when erformed in the appropriate pat...
Study of anxiety and depression in patients undergoing maintenance hemodialysis for chronic renal failure
Background: End-stage renal disease (ESRD) is the most advanced stage of kidney failure in which kidney function is irreversibly lost. Incidence of ESRD have increased in recent times due to increase in life expectancy a...
Attempted suicide in psychiatric emergency patients presenting at a tertiary care hospital
Background: India has been seeing a rise in deaths due to suicide in the recent years1. 17% of the 8, 00, 000 suicides committed worldwide every year are by Indians. The suicide attempts outnumber the completed suicides....