PULMONARY FUNCTION TEST IN PATIENTS WITH SUBCLINICAL HYPOTHYROIDISM: A STUDY FROM EASTERN INDIA
Journal Title: IJAR-Indian Journal of Applied Research - Year 2019, Vol 9, Issue 9
Abstract
Context: Subclinical hypothyroidism (SCH) is defined by an elevated Thyroid stimulating hormone (TSH) level in presence of normal serum free T4 concentration. Thus serum TSH measurement is the necessary test for diagnosis of mild thyroid failure. Aims: Evaluation of the pulmonary function by spirometry in patients of SCH, correlate the pulmonary function with fT3, fT4, TSH level and assess any change in pulmonary function in patients of SCH following treatment. Settings and Design: Prospective case control study from December 2014 to November 2016 in tertiary medical college of eastern India Methods and Material: 70 patients and 35 age sex matched controls were included in the study. The main outcome measures of the study were based on a comparison of spirometric findings of subclinical hypothyroidism with the control group and change in spirometric parameters after 3 months follow up with levothyroxin replacement. Statistical analysis used: The statistical comparisons were done by SPSS software version 20. P value was considered significant if <0.05. Results: The study population 90% were females and 10% males. The mean TSH of the patients with subclinical hypothyroidism was 11.49±8.44 and that of the control group was 3.22±0.79, it was statistically significant. Forced expiratory volume in 1 second of subclinical hypothyroidism patients was significantly lower than control group. The mean FEV1/FVC% was higher in subclinical hypothyroidism as compared with control. After 3 months of thyroid hormone replacement the TSH level was normalised. With improvement of TSH all the respiratory parameters improved significantly. Conclusions: Though mild restrictive pattern of respiratory function abnormality occurs in subclinical hypothyroidism, it cannot be ignored. Hence they should be evaluated and clinical approaches should be taken accordingly at the earliest.
Authors and Affiliations
Sutar S. B, Mishra S.
Keywords
Related Articles
- EP ID EP649766
- DOI -
- Views 74
- Downloads 0
Health Awareness on Knowledge and Attitude Regarding Blood Donation Among Degree Students of Selected Colleges of Vadodara District
Background: - Blood transfusion saves lives during critical situations, but millions of patients needing transfusion do not have timely access to safe blood The donor is donating for it as it will be used in saving lives...
Ethnomedicinal Plants Used Against Skin Diseases in Asansol Raniganj Coalfield Area of West Bengal, India
Every tribal community in India has some species of ethnomedicinal plants which are considered essential for its survival and well being. Asansol Raniganj coalfield area in West Bengal is an important mineral resource ar...
TO COMPARE EFFICACY OF DEXMEDETOMIDINE AND TRAMADOL IN TREATING POST SUBARACHNOID BLOCK SHIVERING AND THEIR SIDE EFFECTS.
Background: Shivering is a frequent complication of regional anaesthesia. This study aimed to compare efficacy of Dexmedetomidine and Tramadol in treating post subarachnoid block shivering and their side effects. Methods...
Prevalence of Dental, Skeletal and Non-Skeletal Fluorosis in Children of Jaipur District of Rajasthan
The study of dental, skeletal and non skeletal fluorosis in the children (6-14 years) was conducted in the two blocks (a) Palera, Heerawala, Nayabas, Saipur and Birasana of Jamwaramgarh block, (b) Chitanukalan,Jugalpura,...
SOCIO-CULTURAL PERCEPTIONS AND PRACTICES AROUND MENARCHE: A STUDY AMONG SCHEDULE CASTE COLLEGE STUDENTS IN TAMIL NADU, INDIA
Though, menstruation is a natural and physiological process for all healthy adult women as ever it has been surrounded by secrecy and myths in many societies. With this in mind, this paper made an attempt to study the so...