Pyrenacantha staudtii Hutch and Dalz (Icacinaceae): A review of Phytochemistry, Pharmacology and Future Perspectives
Journal Title: Tropical Journal of Natural Product Research - Year 2017, Vol 1, Issue 1
Abstract
Various parts (stem bark, leaves and roots) of Pyrenacantha staudtii Hutch and Dalz, Icacinaceae are used traditionally in Nigeria and other West and Central African folk medicine in the treatment of various ailments. Databases of Scifinder, Pubmed, Google Scholar, and Medline were explored for original studies using the following search terms and the combinations thereof: Pyrenacantha, Pyrenacantha staudtii, phytochemical screening, isolated compounds, pharmacological activities, toxicity and ethnomedicinal uses. Search results were collated and studied, extracting relevant results to the aim of this review. The search involves all publications available (originally or translated) in English language till date. The study revealed that different parts of P. staudti have been used in Nigeria ethnomedicine, the Cameroons and other African countries in the management of disease conditions such as malaria, cancer, intestinal colic, threatened abortion, gout, inflammations, convulsions, menstrual disorders, ulcers and sleep disorders, in the form of decoctions, pastes and concoctions. These ethnomedicinal uses have also been scientifically validated by various researchers. The results of this study do not only provide a concise overview on ethnomedicinal uses and pharmacology (anticancer, tocolytic, antiulcerogenic, antimalaria, insecticidal etc.) of various parts of P. staudtii but also the current stage of research on this rarely mentioned plant. It also set forth future perspectives, providing grounds for further scientific exploration of its bioactive constituents with a view of identifying drug leads and or new chemical entities.
Authors and Affiliations
Vincent Imieje
Keywords
Related Articles
- EP ID EP349613
- DOI 10.26538/tjnpr/v1i2.2
- Views 96
- Downloads 0
Antiplasmodial and Acute Toxicity Studies of Fractions and Cassane-Type Diterpenoids from the Stem Bark of Caesalpinia pulcherrima (L.) Sw.
Received 08 March 2018 Revised 01 April 2018 Accepted 04 April 2018 Published online 07 April 2018 Malaria is a major public health disease affecting millions of people worldwide especially in subSaharan Africa, with a...
Human Health Risk Assessment in Relation to Heavy Metals in The Atlantic Mackerel (Scomber scrombrus, L. 1758) Sold in Some Major Markets in Benin City, Nigeria
The study determined the concentrations of Zinc (Zn), Copper (Cu), Lead (Pb), Cadmium (Cd) and Chromium (Cr) in the Atlantic Mackerel (Scomber scrombrus) of mean length 25.54 ± 1.35 cm and mean weight 195.22 ± 1.15 g, fr...
Assessment of Serum Parameters After 28-day Oral Daily Administration of Methanol Leaf Extract of Laggera aurita (Linn) in Wistar Rats
Lagerra aurita is widely used in traditional medicine to treat various ailments in African countries like Nigeria, Senegal and Ghana. It has been reportedly used for the treatment of fever, pain, epilepsy, dyspepsia and...
Profile of Micronutrients, Electrolytes, Haematology and CD4 Count in HIV Infected Subjects on Highly Active Antiretroviral Therapy
Received 22 November 2017 Revised 28 December 2017 Accepted 01 January 2018 Published online 07 January 2018 Human Immunodeficiency Virus (HIV) infection compromises the immune status, diminishes micronutrients availab...
Secondary Metabolites from Curvularia sp, An Endophytic Fungus Isolated from the Leaves of Picralima nitida Durand and Hook (Apocynaceae)
Received 05 March 2018 Revised 25 April 2018 Accepted 05 May 2018 Published online 10 May 2018 Nature has remained a major source of pharmacologically active compounds used for the treatment of new and existing diseases...