Pyrexia of Unknown Origin: A Perplexing Case

Journal Title: Journal of Clinical and Diagnostic Research - Year 2019, Vol 13, Issue 4

Abstract

ABSTRACT Pyrexia of Unknown Origin (PUO) is a common diagnostic dilemma in the medical wards. We present the case of a 64-year-old man who had presented with fever, fatigue, dry cough and bloody diarrhea. Over the next few days, he developed severe testicular pain and renal failure. Blood results revealed anaemia, raised ESR, negative ANA and negative ANCA. Renal biopsy showed crescentic glomerulonephritis. Repeat value of c-ANCA was positive which clinched the diagnosis of Granulomatosis with Polyangiitis (GPA). We present this case in order to illustrate the masquerading nature of the vasculitic syndromes and to emphasise the need to integrate clinical and laboratory clues to reach a diagnosis.

Authors and Affiliations

Kiren George Koshy, Moothezhathu Kesavadas Suresh, Jithin John, Karthik Vijayakumar, Krishnakumar Madhavan

Keywords

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  • EP ID EP553366
  • DOI 10.7860/JCDR/2019/40936.12785
  • Views 84
  • Downloads 0

How To Cite

Kiren George Koshy, Moothezhathu Kesavadas Suresh, Jithin John, Karthik Vijayakumar, Krishnakumar Madhavan (2019). Pyrexia of Unknown Origin: A Perplexing Case. Journal of Clinical and Diagnostic Research, 13(4), 7-8. https://europub.co.uk/articles/-A-553366