Pyridoxine: The ‘Ba.Six’ of use in Nausea and Vomiting of Pregnancy
Journal Title: Journal of Clinical and Diagnostic Research - Year 2019, Vol 13, Issue 5
Abstract
ABSTRACT Over the centuries, the dietary and biochemical essentiality of pyridoxine in the humans has been well established. Apart from various physiological functions, pyridoxine is therapeutically important in Nausea and Vomiting of Pregnancy (NVP). Pyridoxine on its own or a combination of pyridoxine (vitamin B6) (pregnancy category A) and doxylamine (category B), previously available as Bendectin, is the only medication that is specifically labeled for the treatment of NVP by the Food and Drug Administration. Although various reports claims the efficacy of pyridoxine in NVP, there are a very few studies on its mechanism of action in relieving the symptoms. Therefore, the present review was aimed at revisiting relevant previous data and providing the necessary background to discuss the chemistry, pharmacochemistry, status in pregnancy and mechanism/s of action in NVP of this B-complex vitamin in detail.
Authors and Affiliations
Abbas Hassan, Arun Kumar Dubey, Malpe Surekha Bhat
Keywords
Related Articles
- EP ID EP582922
- DOI 10.7860/JCDR/2019/40826.12855
- Views 116
- Downloads 0
Root Coverage of Class III Recession using Free Gingival Graft using Novel Root Coverage Esthetic Score
ABSTRACT A variety of regenerative procedures has been used for the correction of gingival recession defects. However, root coverage can be quite challenging in cases of deep and wide Miller’s class III recession defects...
Snake Venom, an Unbeheld Drug for Nipah Virus? A Lead from Ayurveda
ABSTRACT Newly emerging viral fevers are affecting the people all over the world. Recently Nipah outbreak occurred in Kerala (May 2018) and claimed many deaths. Anti-viral drugs for these dangerous viruses have not been...
A Perplexing Case of Cellular Leiomyoma with Excessive Myxoid Degeneration
Uterine leiomyomas are the most common benign lesions of the uterus. This tumour can vary in size, location, presentation and degenerations. In most cases, they are easy to diagnose clinically with help of imaging. We pr...
Providencia Rettgeri: An Emerging Nosocomial Uropathogen in an Indwelling Urinary Catheterised Patient
Providencia rettgeri (P. rettgeri) is an ubiquitous organism but is seldom associated with human disease. We report the isolation of P. rettgeri from the urine sample of a 39-year-old male patient on prolonged Foley’s ca...
Dengue Haemorrhagic Encephalitis: Rare Case Report with Review of Literature
Dengue is an endemic arboviral infection prevalent especially in tropical countries including Southern and Southeast Asia. Central Nervous System (CNS) involvement in dengue infection is uncommon. Haemorrhagic encephalit...