Pyridoxine: The ‘Ba.Six’ of use in Nausea and Vomiting of Pregnancy
Journal Title: Journal of Clinical and Diagnostic Research - Year 2019, Vol 13, Issue 5
Abstract
ABSTRACT Over the centuries, the dietary and biochemical essentiality of pyridoxine in the humans has been well established. Apart from various physiological functions, pyridoxine is therapeutically important in Nausea and Vomiting of Pregnancy (NVP). Pyridoxine on its own or a combination of pyridoxine (vitamin B6) (pregnancy category A) and doxylamine (category B), previously available as Bendectin, is the only medication that is specifically labeled for the treatment of NVP by the Food and Drug Administration. Although various reports claims the efficacy of pyridoxine in NVP, there are a very few studies on its mechanism of action in relieving the symptoms. Therefore, the present review was aimed at revisiting relevant previous data and providing the necessary background to discuss the chemistry, pharmacochemistry, status in pregnancy and mechanism/s of action in NVP of this B-complex vitamin in detail.
Authors and Affiliations
Abbas Hassan, Arun Kumar Dubey, Malpe Surekha Bhat
Keywords
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- EP ID EP582922
- DOI 10.7860/JCDR/2019/40826.12855
- Views 107
- Downloads 0
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