QUADRANT WISE ANALYSIS OF RNFL THICKNESS MEASURED BY OPTICAL COHERENCE TOMOGRAPHY (OCT) IN PRIMARY OPEN ANGLE GLAUCOMA (POAG) AND ITS ABILITY TO DETECT GLAUCOMA
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2015, Vol 2, Issue 12
Abstract
PURPOSE: To study the RNFL thickness measured by stratus optical coherence tomography (OCT) patients with primary open angle glaucoma (POAG) and normal subjects, analyse the quadrant which is most efficient parameter for detecting glaucomatous damage and its correlation with visual fields. MATERIAL AND METHODS: This is a cross-sectional study of 50 glaucomatous eyes and 50 normal subjects. RNFL thickness was measured in different quadrants using stratus optical coherence tomography. RESULTS: The RNFL thickness measured by OCT in 50 glaucomatous and 50 normal eyes showed that the Inferior RNFL thickness in POAG is 77.54±31.11 compared to normal subjects where Inferior RNFL thickness is 124.96±16.74 (P<0.001). The Superior RNFL thickness in POAG is 78.32±34.81 compared to normal subjects where Superior RNFL thickness is 113.86±15.07 (P<0.001). The Nasal RNFL thickness in POAG is 53.52±13.88 compared to normal subjects where Nasal RNFL thickness is 78.103±17.87 (P<0.001). The Temporal RNFL thickness in POAG is 49.72±18.01 compared to normal subjects where Temporal RNFL thickness is 60.17±12.15 (P<0.001). The Average RNFL thickness in POAG is 63.94±18.01 compared to normal subjects where Average RNFL thickness is 97.97±9.59 (P<0.001). Both mean deviation (MD) and pattern standard deviation (PSD) showed a significant correlation with all the RNFL thickness parameters in eyes with glaucoma (pearson correlation coefficient >0.4). CONCLUSION: RNFL thickness measured on OCT may serve as useful adjunct in accurately detecting glaucoma. Average and inferior RNFL thicknesses are among the most efficient parameters for detecting glaucoma correlating with the visual field changes.
Authors and Affiliations
Nishant Sultana, Swati Pillai
Keywords
Related Articles
- EP ID EP226675
- DOI 10.18410/jebmh/2015/248
- Views 86
- Downloads 0
A CROSS SECTIONAL STUDY ON THE PROFILE OF FOOD ALLERGY AMONG PATIENTS WITH CHRONIC URTICARIA IN KERALA
BACKGROUND Skin allergy in the form of urticaria is commonly encountered. Food allergy is one of the common aetiologies responsible for this clinical situation. Identifying the offending allergens and avoidance is one of...
CARDIAC INVOLVEMENT IN CHRONIC KIDNEY DISEASE
BACKGROUND At every stage of CKD, cardiovascular disease is the leading cause of morbidity and mortality with 30 to 45% of patients advancing to cardiovascular complications. (3) The aim of the study was to evaluate the...
THE VALUE OF ROUTINE NUCHAL TRANSLUCENCY IN DETECTION OF CHROMOSOMAL ANOMALIES IN A LOW RISK POPULATION
BACKGROUND Every pregnant woman desires a healthy child who is free of anomalies. In general population, the overall risk of having a child with a major malformation is 3% to 5%. The ability conferred by the increasing s...
INTRAUTERINE FETAL DEATH CASES AT TERTIARY CENTER
BACKGROUND Intrauterine fetal death is a tragic event for the parents and a great cause of stress for the caregiver. It is an important indicator of maternal and perinatal health of a given population. This study was und...
A STUDY ON ADDITIVE ASSOCIATION OF LIPOPROTEIN (A) AND HOMOCYSTEINE IN ACUTE ST SEGMENT ELEVATION MYOCARDIAL INFARCTION
BACKGROUND Prevalence of Coronary Artery Disease (CAD) is increasing in India. Acute myocardial infarction has very high morbidity and mortality, hence economically a big burden. However, established risk factors alone d...