Quality of Life Allergic Rhinitis after Probiotic Combination Supplementation
Journal Title: SAINS MEDIKA (Journal of Medicine and Health) - Year 2012, Vol 4, Issue 2
Abstract
Background: Probiotics are potential as a therapy for allergy sufferers, which can increase the ratio IFNγ, IL4. However, the effects of probiotics on the quality of life of patients with allergic rhinitis have not been developed yet. This study aimed to determine the effect of a combination of probiotics on the quality of life of patients with allergic rhinitis. Design and Methods: This study used a randomized design with post test control group design. The populations in this study were men and women aged 18-25 years who suffer from allergic rhinitis with moderate to severe according to the WHO criteria. This study uses two groups: the group treated by administration of a combination of probiotics and the control group were given a placebo. Quality of life was assessed by checklist scores and levels of IgE. Data were analyzed using the Mann Whitney U test with 95% confidence intervals. Results: The results of statistical analysis showed no significant difference between the quality of life of allergic rhinitis sufferers control and treatment groups (p> 0.05). However, there are significant differences between the mean levels of IgE allergy sufferers rhintis control and treatment groups (p <0.05). Conclusion: Probiotic treatment did not affect the quality of life of patients with allergic hinitis but a reduction in the levels of IgE (Sains Medika, 4(2):157-164).
Authors and Affiliations
Andriana Tjitria Widi Wardani, Anita Soraya Soetoko
Keywords
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