Radial glomerular count- An assessment of human nephrogenesis
Journal Title: Indian Journal of Clinical Anatomy and Physiology - Year 2018, Vol 5, Issue 2
Abstract
Introduction The important reason for progression of various glomerulopathies is variable Radial glomerular count RGC There are few studies on the radial glomerular count Therefore we conduct this study with an aim to contribute the knowledge of the human developing kidney by counting radial glomerular numberMaterials and Methods Thirty normal human fetuses of midgestational period 14 to 28 weeks were selected for the study The fetus should not have any congenital anomaly The fetal kidney tissue slides were prepared and stained in hematoxylin and eosin Then numbers of glomerular generations were counted and correlate the data with the different gestational groupsResults The results showed that the average RGC is gradually increasing from 4 to 15 counts in mid gestational age The results suggest significant statistical correlation between the period of gestation and the number of glomerular generations Correlation coefficient value R2 099 The fetal kidney weight and the number of glomerular generations in respective gestational age also shows definite statistical correlationsConclusion The present study concluded that gradually increasing average RGC can express human fetal kidney growth in intrauterine life The histomorphologic assessment of RGC can be used as relatively better method of estimating gestational age The observed growth tendencies of fetal glomerulus in human fetal life by RGC could be useful to assess the kidney maturity in the futureKeywords Glomerulopathies RGC
Authors and Affiliations
Suvarna A. Gulanikar, Savita Kadam, SmitaShinde, G. A. Shroff
Keywords
Related Articles
- EP ID EP475881
- DOI 10.18231/2394-2126.2018.0061
- Views 31
- Downloads 0
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