RADIATION THERAPY– AN EFFECTIVE TOOL FOR ANALGESIA IN METASTATIC BONE DISEASE IN BREAST CANCER
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 61
Abstract
BACKGROUND Radiation therapy plays an important role in the treatment of breast cancer patients with bone metastasis. Approximately 70% of patients are likely to achieve complete pain relief after palliative external beam radiotherapy (RT). The aim of current study is to determine the role of RT in palliation of symptomatic bone metastases from invasive breast cancer. MATERIALS AND METHODS Hundred and twelve breast cancer patients who received palliative RT for bone metastasis were enrolled prospectively. Baseline pain assessment using visual analogue score was done at the time of diagnosis and 3 months following completion of RT. WHO analgesic pain ladder was also used for adequate pain relief. Analgesic requirement was also assessed at the time of diagnosis and 3 months following RT. RESULTS Our results found thoracolumbar spine involvement (87%) to be the commonest site of metastasis. A reduction in severity of pain was noticed with 79.5% patients experiencing mild pain, 16% having moderate pain, and only 3.6% having severe pain after treatment with palliative RT. Approximately 36.6% patients experienced significant reduction in analgesic requirement. CONCLUSION This study provides an insight into the combined use of palliative RT and pharmacological treatment for pain relief in breast cancer patients with bone metastasis. We found palliative RT and adequate analgesic use as strong pillars in managing bone metastasis secondary to breast cancer.
Authors and Affiliations
Preety Negi, Pamela Alice Kingsley, Jaineet Sachdeva, Himanshu Srivastava
Keywords
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