RADIOLOGICAL PREDICTORS OF MORTALITY IN PATIENTS WITH PRIMARY SPONTANEOUS INTRACEREBRAL HAEMORRHAGE
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 18
Abstract
BACKGROUND Primary spontaneous intracerebral haematoma (ICH) is a deadly form of stroke with very high mortality and morbidity. Outcome prediction is mandatory for optimisation of therapeutic efforts. The objective of our prospective study is to identify reliable radiological predictors of mortality from a plain CT study of brain. MATERIALS AND METHODS We prospectively collected clinical and radiological data from 112 patients with primary ICH. Key measurements were taken from the plain CT scan of brain at admission to collect the radiological parameters. Bivariate analysis of clinical and radiological predictors of poor outcome were undertaken using unadjusted logistic regression analysis. Those radiological variables found to have statistical significance on bivariate analysis were analysed using multivariate logistic regression model. The regression model was validated using ROC (Receiver Operating Characteristic) curve. RESULTS The mortality in our series was 28.6% (N= 32). Radiological factors associated with poor outcome on bivariate analysis were volume of haemorrhage, Midline Shift (MLS), Intraventricular Haemorrhage (IVH) and hydrocephalus. On multivariate analysis IVH (P= .007), MLS (.008) and volume of haemorrhage (P= .029) were significantly associated with poor outcome. Using ROC curve, we had a cut-off volume of 42.5 cm3 with an optimum sensitivity of 81.2% and specificity of 90%. CONCLUSION Plain CT study of brain obtained within 24 hours of the ictus can be reliably used for predicting the prognosis of subjects with primary supratentorial ICH.
Authors and Affiliations
Krishnakumar P, Biju Bhadran, Harrison G, Aravind K. R
Keywords
Related Articles
- EP ID EP417272
- DOI 10.14260/jemds/2018/493
- Views 75
- Downloads 0
COMPARISON OF EFFICACY OF PLAIN LIGNOCAINE WITH LIGNOCAINE AND CLONIDINE IN INTRAVENOUS REGIONAL ANAESTHESIA FOR UPPER LIMB SURGERY
[b] INTRODUCTION[/b]: IVRA is a simple, reliable, and effective technique with rapid onset of action, rapid and prompt recovery after tourniquet release. It provides good analgesia, adequate muscle relaxation, &...
AN IN VITRO COMPARATIVE EVALUATION OF DENTINAL TUBULE OCCLUSION BY CURRENT DESENSITIZING AGENTS- A SCANNING ELECTRON MICROSCOPIC STUDY
BACKGROUND Increasing life expectancy coupled with effective treatment options for dental caries and periodontal disease has enabled patients to retain their natural teeth for prolonged periods. Dentinal hypersensitivity...
ANTIMICROBIAL SUSCEPTIBILITY PATTERN OF BACTERIAL AND FUNGAL OCULAR ISOLATES FROM TERTIARY CARE OPHTHALMIC HOSPITALS IN CHENNAI
BACKGROUND Infectious keratitis is an ophthalmic emergency that needs immediate institution of treatment. Recent studies have shown increasing evidence of resistance of microbes to antimicrobial agents, which have furthe...
VACUUM ASSISTED HYDROCOLLOID DRESSING – OUR EXPERIENCE
BACKGROUND Chronic ulcers are responsible for significant morbidity and mortality all over the world. Management of these ulcers is constantly updated with newer advancements and newer dressing materials. Vacuum-assisted...
PARENTAL NUTRITION MODEL AND CHILDREN’S NUTRITIONAL BEHAVIOURS
BACKGROUND Human beings need nutrition to maintain their vitality and health. Today’s life has affected and mostly disturbed people’s dietary habits, causing various anomalies and diseases in their bodies. So, humans nee...