Raised C-Reactive Protein In Cerebrospinal Fluid: A Diagnostic Marker Of Bacterial Meningitis
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 1
Abstract
Objective: To establish diagnostic role of CSF C-reactive protein quantitively in meningitis. Method: This prospective study was done on 50 patients. According to serum & CSF analysis 28 cases had pyogenic meningitis 22 cases had aseptic meningitis. Along with other appropriate investigations, quantitative CSF C- reactive protein(CRP) was assayed and data were analysed to set a diagnostic level and sensitivity and specificity of CSF –CRP in meningitis. Result::The differences in the mean values were statistically significant for CSF protein levels, CSF leukocyte count, and CSF/serum glucose between bacterial and aseptic meningitis groups (p<0.001). Values of serum CRP had significant difference in bacterial meningitis group compared to other group (p<0.001). Conclusion: CSF CRP can easily differentiate bacterial meningitis from other meningitis with great sensitivity and specificity .
Authors and Affiliations
Chinmoy Barik, Priyanka Gupta, Kishore Shaw
Keywords
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- EP ID EP439922
- DOI 10.9790/0853-1801091723.
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