Randomized Controlled Trial Comparing Open, Conventional, and Single Port Laparoscopic Appendectomy

Journal Title: Journal of Clinical and Diagnostic Research - Year 2017, Vol 11, Issue 10

Abstract

Introduction: Open appendectomy took decades to evolve to establish itself as the treatment for appendicitis. Then came the era of laparoscopy, which unlike in case of cholecystectomy, faced quite resistance and still has not become the treatment of choice. What followed was the reduction in the size and number of ports. Single port laparoscopic appendectomy and Natural Orifice Transluminal Endoscopic Surgery (NOTES) were the further developments. Aim: To evaluate the status of appendectomy in patients with simple appendicitis through the three approaches: Open Appendectomy i.e. OA, Conventional Laparoscopy Appendectomy i.e. CLA and Single Port Laparoscopic Appendectomy (SPLA)/Incision Approach. Materials and Methods: The study was designed as a double blinded randomised controlled trial and included the patients aged 12-50 years who had simple uncomplicated appendicitis and underwent appendectomy over a duration of 18 months. Results: Mean age of patients was 31.27, 27.4 and 27.64 years and female to male ratio was 1.14, 1.5 and 1.33 for OA, CLA and SPLA arm, respectively. Overall duration of presentation was two days and most of the patients were under BMI of 25. The appendix was the first visualized organ in less than half of the total patients and a little over half had adhesions. The most common location of the appendix was paracaecal followed by pelvic. There were very few intraoperative complications like bleeding from appendicular artery and spillage from appendix in one patient who underwent OA. Mean duration of surgery was 65.18 minutes (SPLA>CLA>OA). Surgery took less time in patients with BMI<25 (SPLA>CLA>OA). CLA took substantially less time (49.5 minutes) in patients with BMI≥25 (CLA>OA>SPLA). Pain was significantly higher in minimal invasive procedures compared to OA in immediate postoperative period, which settled 4th hour onwards and remained on higher side for patients who underwent OA. Three fourth patients were able to accept orally after six hours. Wound infection rate was low (OA>CLA=SPLA). Patients who underwent OA stayed in hospital for a longer time and resumed their duty much later compared to minimal invasive arm. Scar assessment score and overall satisfaction were not much different among the patients with simple appendicitis of three arms. Cost of treatment was significantly higher for SPLA compared to other treatment arms. Conclusion: In patients with simple uncomplicated appendicitis, OA, CLA and SPLA do not differ much in outcome especially in lean and thin patients.

Authors and Affiliations

Varun Kumar Singh, Kumar Nishant, Bikram Kharga, Aboni Kumar Kalita, Phuchungla Bhutia, Jatin Jain

Keywords

Related Articles

Assessment of Non-surgical Periodontal Therapy on IL-22 and S100A12 Concentration in Gingival Crevicular Fluid

ABSTRACT Introduction: Periodontitis is a disease of the periodontal tissues that results in attachment loss and destruction of alveolar bone. Several risk factors such as bacteria, the host immune responses and genetics...

Chronic Kidney Diesease-Economic Impact: A Vietnamese Hospital Perspective, 2014–2017

ABSTRACT Introduction: Chronic Kidney Disease (CKD) has a high morbidity and mortality in developing countries. A cost analysis is needed to inform the economic evaluations for prevention strategies and treatment options...

Stenotrophomonas maltophilia mimicking Klebsiella on Chromogenic Media

Chromogenic media are being used now-a-days for identification of many microorganisms in the clinical microbiology laboratories. They are being used for screening purposes especially in case of urine cultures, environmen...

Utility of Acridine Orange Fluorescence Microscopy in Cytodiagnosis of Oral Lesions

ABSTRACT Introduction: Oral exfoliative cytology is a reasonably effective technique for rapid initial evaluation of suspicious lesions. Exfoliated cells obtained from saliva, lavage or scrapings are ideally stained with...

Enhancing Knowledge Integration in Biochemistry among Undergraduate Medical Students through Active Learning Strategy

ABSTRACT Introduction: Medical education today, encourages modification of traditional didactic lectures with innovations to promote active learning strategies to enhance integration of knowledge and critical thinking sk...

Download PDF file
  • EP ID EP364875
  • DOI 10.7860/JCDR/2017/25671.10762
  • Views 95
  • Downloads 0

How To Cite

Varun Kumar Singh, Kumar Nishant, Bikram Kharga, Aboni Kumar Kalita, Phuchungla Bhutia, Jatin Jain (2017). Randomized Controlled Trial Comparing Open, Conventional, and Single Port Laparoscopic Appendectomy. Journal of Clinical and Diagnostic Research, 11(10), 5-10. https://europub.co.uk/articles/-A-364875