Rare Extrapulmonary Tuberculosis in Immunocompetent Adults: Experience of a Tertiary Hospital
Journal Title: European Archives of Medical Research - Year 2019, Vol 35, Issue 3
Abstract
Objective: Tuberculosis (TB) is an infection that can involve all tissues and organs. Although pulmonary TB (PTB) is more common, extrapulmonary TB (EPTB) is still a major clinical problem. The incidence of EPTB is 35.1% and in recent years; there has been an increase in EPTB case reporting in our country. In this study, we retrospectively investigated the clinical and laboratory characteristics of rare EPTB cases. Methods: The study included rare EPTB patients diagnosed and/or followed up in our clinic. Cases with pleural TB and lymph node TB were excluded from the study. The diagnosis of EPTB was made by clinical, microbiological and/or histopathological and/or radiological findings and response to treatment. The demographic features, clinical findings and laboratory values were recorded from patient files, and were evaluated in terms of EPTB. Results: Fifty patients were included in the study (mean age=34±15.8 years, female/male=33/17). The most frequently involved organ was peritoneum (n=13, 26%). There was multi-organ involvement in 4 cases (8%). Co-existence of EPTB with PTB was determined in 9 cases (18%). Four patients had a history of TB and 14 had a history of contact with TB. All the cases were human immunodeficiency virus-negative, and one case was hepatitis B surface antigen positive. The major complaints were abdominal pain, weight loss, night sweats, fever, and cough. Twenty-three patients had normal chest radiographs and the mean duration of treatment was 9 months. Conclusion: TB is a serious public health problem in Turkey as well as all over the world. Since it is a treatable disease, early diagnosis and treatment have utmost importance for avoiding the serious complications of rare EPTB forms.
Authors and Affiliations
Sinem Güngör, Özlem Soğukpınar, Murat Yalçınsoy, Bilgen Begüm Afşar Dönmez, Olga Akkan, Esra Akkütük Öngel, Esra Usta Bülbül, Esen Akkaya
Keywords
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