RAT KIDNEY TISSUES: OXIDATIVE MODIFICATION OF PROTEINS UNDER WATER AND SALT LOADS ASSOCIATED WITH HgCl2 NEPHROPATHY
Journal Title: Food and Environment Safety - Year 2018, Vol 0, Issue 3
Abstract
Some changes in the main indexes of the pro-oxidation system of rat’s kidney tissues exposed to water and salt load on background of the nephropathy caused by mercury chloride were investigated. Conditions of the free-radical oxidation of kidney tissues’ proteins under water and salt load alone or complicated by the nephropathy have been analyzed. It is found that water and salt load leads to a higher content of the thiobarbiturate reaction products (TBA-RP) in kidney tissues in comparison with the control experiments while the content of the protein oxidative modification products remains unchanged. Thus, water and salt load causes a higher activation level of free radical oxidation of lipids. A histochemical investigation has been performed to evaluate a degree of the oxidative modification of proteins in rat kidney tissues under water and salt load complicated by the mercuric nephropathy and a higher level of the oxidative modification of proteins has been determined by the Red/Blue coefficient in rat kidneys irrespectively of the load type in case of intoxication with mercury chloride.
Authors and Affiliations
Alla VELYKA
Keywords
Related Articles
- EP ID EP552178
- DOI -
- Views 126
- Downloads 0
WATER CHEMICAL ANALYSIS OF WELLS IN THREE SETTLEMENTS OF SUCEAVA PLATEAU, ROMANIA
Water from wells in Humoreni, Comănești and Soloneț (Suceava County, Romania) was sampled in order to measure the concentration of ammonium, nitrite, nitrate, orthophosphate and sulfide. The measured values were used to...
ANTIOXIDANT CAPACITY OF LOCAL BERRIES IN COMPLEX FOOD PRODUCTS
Complex food degradation is caused by lipid oxidation process and as a result there may occur a rancid odor, colour change and texture may be modified, thus negatively influencing the sensory qualities of food. The resu...
MODERN ASPECTS OF MARKETING RESEARCH APPLICATION AS DETERMINANT OF PROMOTIONAL MIX IN BUSINESS ENTITIES FROM MILK PROCESSING INDUSTRY IN THE REPUBLIC OF MACEDONIA
The basis of marketing concept refers to the fact that companies exist in order to satisfy consumers’ needs. In order to achieve its objectives and be successful, a company needs to be aware of its customers’ wishes and...
VALIDATION OF A HIGH PERFORMANCE LIQUID CHROMATOGRAPHY METHOD FOR CARBENDAZIM RESIDUES QUANTIFICATION IN TOMATOES
A high performance liquid chromatography method for carbendazim residues determination was adapted to the condition of our laboratory and validated for tomatoes samples. Carbendazim eluted at 3.13 minutes. The signal was...
EFFECT OF ACID TYPE AND PARTICLE SIZE ON THE YIELD AND PURITY OF APPLE (MALUS DOMESTICA ‘FĂLTICENI’) POMACE PECTIN
This work proposes the use of Malus domestica ‘Fălticeni’ pomace, resulted from the processing of apples into juice in the geographical area of Fălticeni, Suceava (Romania), as a source for pectin extraction. Pectin was...