Rate Pressure Product in Diabetic Cardiac Autonomic Neuropathy at Rest and Under Stress
Journal Title: International Journal of Research and Review - Year 2018, Vol 5, Issue 9
Abstract
Introduction: Rate pressure product, a non invasive indicator of myocardial oxygen demand tends to increase with stress. This determinant is less studied in diabetic cardiac autonomic neuropathy patients both at rest and after stress. An insight into this determinant of myocardial oxygen demand in diabetic cardiac autonomic neuropathy patients may explain sudden adverse cardiovascular events in such patients. Methods: Case control study (n=45) was done on thirty age matched (40-60 yr) type 2 diabetics with/ without diabetic cardiac autonomic neuropathy and fifteen controls for rate pressure product. Results: Results demonstrated (ANOVA and paired ‘t’ – test, ‘SPSS’ software) that resting rate pressure product was significantly increased in cardiac autonomic neuropathy patients (p< 0.05) and out of normative zone (>12) pushing these patients into risk zone for adverse cardiovascular events. The stress rate pressure product was similar to resting showing little or no increment demonstrating a non significant result (p>0.01) Conclusion: Diabetic cardiac autonomic neuropathy significantly increases resting rate pressure product and inversely affects stress related increment for same.
Authors and Affiliations
Dr. Rishu Segan
Keywords
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