Recent Advances and Developments in Cochleate Technology
Journal Title: Nanomedicine & Nanotechnology Open Access - Year 2017, Vol 2, Issue 2
Abstract
Cochleates are lipid based cylindrical solid particulates formed by rolling of large continuous bilayer sheets. They are promising drug delivery vehicles with sustained release capabilities and show improved bioavailability, efficacy as well as reduced toxicity of encapsulated drugs. They are known to be stable and hence enhance the quality of drug formulation by increasing the shelf-life of the formulation. Their nano- to sub-micrometer size range allows for delivery through various routes of administration. This review highlights recent advancements in cochleate technology with respect to their composition, self-assembly, formulation and a brief account of their applications.
Authors and Affiliations
Judeh ZMA, Nagarsekar K, Shuddhodana A
Keywords
Related Articles
- EP ID EP282682
- DOI 10.23880/nnoa-16000119
- Views 104
- Downloads 0
Comparison of the Structural Electrical and Optical Properties of CdS Films Deposited by Chemical Bath Deposition and Spray Pyrolysis
Cadmium sulphide (CdS) thin films were obtained by two methods: chemical bath deposition (CBD) and spray pyrolysis (SP). The influence of the preparation technique on the structural, electrical and optical properties of...
Carbon nanotubes for "Ionic Wind" Craft or "Ionocraft"
Peter Thiel of the Founders Fund once famously said, "We wanted flying cars, and we got 140 characters."But nanotechnology now does make possible the long desired flying cars. It's a different propulsion method though th...
ZnO Doped Graphite Nanocomposite via Agathosma Betulina Natural Extract with Improved Bandgap and Electrical Conductivity
This contribution reports for the first time on green synthesized Zinc Oxide graphite doped (ZnO/G) material that was fabricated and exposed to UV lamp irradiation at 250 nm for 4 hrs. The morphology and the structure of...
Nanosilver Enabled Reactive Dyes for Antimicrobial Medical Textiles
The present study describes the preparation technique for silver nanoparticles incorporated fabrics for enhanced antimicrobial property to be used in textile applications. The silver nanoparticles were prepared by the re...
Efficiencies of the Cryoprotectants N-Methylacetamide, N-Methylformamide and Dimethyl Sulfoxide, and the Cell Protectants Trehalose and Hydroxyethyl Starch in Cryopreservation of Swine Sperm
Polar molecules protect against freeze-induced damage by interfering with the polarised water arrangement during ice nucleation inside cells. Insufficient protection from freeze-induced damage (acting during freezing) an...