Recent advances and future trends in zebrafish bioassays for aquatic ecotoxicology
Journal Title: Ecocycles - Year 2018, Vol 4, Issue 2
Abstract
Zebrafish (Danio rerio), a cyprinid teleost, has become an ideal model species for aquatic ecotoxicology due to the broad spectra of methodologies that have been developed since the 1980s. The zebrafish has many advantages as a model organism e.g. small size, ex utero development of the embryo, short reproductive cycle, and transparent embryos. In addition, the zebrafish shares a high degree of homology with the human genome. It has become a powerful model organism for genetics, development, environmental toxicology, several human diseases and pharmacology. Zebrafish bioassays can be used for environmental monitoring including pollutant evaluations, such as toxic heavy metals, endocrine disruptors, and organic pollutants. The large number of transparent embryos gained from zebrafish females, in vitro and rapid embryonic development and ready-to-use methods of biotechnology enables us to use mostly automatized high-throughput screening not only in pharmaceutical drug development protocols but in aquatic ecotoxicology as well.
Authors and Affiliations
Istvan Magyary
Keywords
Related Articles
- EP ID EP450192
- DOI 10.19040/ecocycles.v4i2.108
- Views 112
- Downloads 0
Attempt to assess tourist products in rural areas based on the Kano method as basis of customer experience
Rural tourism, which is at the same time a kind of broadly understood sustainable tourism, is a concept, although widely used, difficult to define. Many researchers such as M. Jansen-Verbeke distinguish between rural tou...
Geographical and ecological outline of metal(loid) accumulating plants in Italian vascular flora
The decontamination of heavy metal polluted soils is one of the major challenges that our industrialized world has to face. Remediation technologies are being developed and employed in order to reduce the potential hazar...
Anthropogenic soils: general aspects and features
In recent decades man's role in soil formation has become a matter of great concern among soil scientists. Man is now considered a soil-forming factor and anthrosolization is recognised as a soil-forming process that con...
Soil use practices for sustainable agricultural land and water management
This paper presents experimental results focused on measures increasing water infiltration into the soil profile and higher water holding capacity of the land. It is important from soil and land protection point of view...
Effects of foliar biofertilization on the quality parameters of apple (Malus domestica Borkh.)
Nowadays the main task of scientists is to find natural ways of improving plant productivity that lead to environmentally friendly agriculture. Biofertilizers have a great potential to achieve this aim but unfortunately...