RECENT ADVANCES AND PATENTS OCULAR DRUG DELIVERY SYSTEM
Journal Title: World Journal of Pharmaceutical Research - Year 2017, Vol 6, Issue 9
Abstract
Background- A wide variety of drug delivery system have been developed to treat the disease of eye. Some traditional ocular drug delivery system is used but it has some disadvantages is to eliminate from the anterior part of eye and lack of retention time of contact with eye due to specific anatomy and physiology barrier of eye. Objective- The main objective of the study to review the recent advance and patent nanoformulation for ocular drug delivery system. as well as various therapies which are targeted into gene and protein of anterior part of eye to treat the genetic disorder of eye with specific rout of administration. Result- Recently advance ocular drug delivery system have been developed to produced controlled drug release into eye segments. The most powerful advantage of recent drug delivery system over the traditional drug system is to increase solubility of poor soluble drugs into eye and cross the various barrier of the eye to reached the anterior parts as well as posterior parts of eyes. Conclusion- FDA website described that only 21 ocular drugs were approved in the last 10 years; 30 new drugs last back to 1995. No ocular drugs were approved in 1995 or 2003. It is proved that efficiency of nanoparticles for ocular drug delivery is much better than other novel drug delivery systems in terms of dose, stability, cell targeting, particle size etc. Nanohydrogel, lipid nanoparticles, nanosuspension, etc. are being used successfully in ocular nanotechnology.
Authors and Affiliations
Neha Neha
Keywords
Related Articles
- EP ID EP618115
- DOI -
- Views 152
- Downloads 0
MYELOID SARCOMA AS THE PRESENTING SYMPTOM OF CHRONIC MYELOID LEUKEMIA CHRONIC PHASE: A CASE REPORT
Myeloid sarcoma is an extramedullary tumor of immature granulocytic cells. It is a rare condition; most often associated with acute myeloid leukemia but can be associated with myeloproliferative neoplasms or myelodysplas...
AN INSIGHT OF THE ROLE OF VITAMIN D ON SKIN DISEASES
Vitamin D is one of the most essential hormones in the human body which is produced by epidermal keratinocytes under the effect of the sun’s radiation {Ultraviolet B}. Further, 25{OH}2D3 is the inactive form of vitamin D...
RADICAL SCAVENGING POTENTIAL OF COMPOUNDS FROM MELALEUCA ERICIFOLIA SM.
Plants belonging to genus Melaleuca are economically important plants as the leaves of most species contain volatile oils. In this study, the non-volatile constituent of the leaf and bark of Melaleuca ericifolia Sm. grow...
KNOWLEDGE ATTITUDE AND PRACTICES REGARDING VIOLENCE AGAINST WOMEN AMONG A SAMPLE IN PRIMARY HEALTH CARE CENTERS IN BAGHDAD CITY
Background: Violence against women defined by the united Nations “ any act of gender based violence (GBV) that results in, sexual, physical, or harm of mental or suffering to women including: threats of such acts, coerci...
ACUTE AND SUB-ACUTE TOXICITY EVALUATION OF DISULPHIDE DERIVATIVE OF DIHYDROARTEMISININ
Dihydroartemisinin (DHA), the active metabolite of artemisinins, possesses anticancer activity but its usefulness may be limited by its short half-life. Recently, a persulphide (or disulphide) derivative of DHA (sDHA) ha...