Recent Advances in Diagnosis of Tuberculosis: A Review
Journal Title: SSR Institute of International Journal of Life Sciences (SSR-IIJLS) - Year 2018, Vol 4, Issue 1
Abstract
Globally tuberculosis remains a challenge from the point of diagnosis, detection of drug resistance, and treatment. Treatment can only be initiated, when infection is detected and it based on the results of AST, recently there has been a marked increase in the development and testing of novel assays designed to detect Mycobacterium tuberculosis. Although most important advances that would develop tuberculosis (TB) analysis have not been realized, we are beginning to see the innovations that have been prompted by the recognition of the economic potential of the market for new diagnostic tests for TB and considerably increased public and private funding and awareness. In this present review, we focused on the newer tests that are accessible for the analysis of suppressed and active tuberculosis and rapid detection of drug resistance, nucleic acid amplification for identification of M. tuberculosis complex, and rapid tests for detecting drug resistance. PCR-based technologies and hybridization assays used for the recognition of the mycobacteria. Though these newer techniques are useful for a rapid result, emphasizing that culture-based diagnosis is still the ‘gold standard’ for the diagnosis and follows up on tuberculosis.
Authors and Affiliations
Shabnam Parveen, Deepa Arya
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