Recent Advances in Diagnosis of Tuberculosis: A Review
Journal Title: SSR Institute of International Journal of Life Sciences (SSR-IIJLS) - Year 2018, Vol 4, Issue 1
Abstract
Globally tuberculosis remains a challenge from the point of diagnosis, detection of drug resistance, and treatment. Treatment can only be initiated, when infection is detected and it based on the results of AST, recently there has been a marked increase in the development and testing of novel assays designed to detect Mycobacterium tuberculosis. Although most important advances that would develop tuberculosis (TB) analysis have not been realized, we are beginning to see the innovations that have been prompted by the recognition of the economic potential of the market for new diagnostic tests for TB and considerably increased public and private funding and awareness. In this present review, we focused on the newer tests that are accessible for the analysis of suppressed and active tuberculosis and rapid detection of drug resistance, nucleic acid amplification for identification of M. tuberculosis complex, and rapid tests for detecting drug resistance. PCR-based technologies and hybridization assays used for the recognition of the mycobacteria. Though these newer techniques are useful for a rapid result, emphasizing that culture-based diagnosis is still the ‘gold standard’ for the diagnosis and follows up on tuberculosis.
Authors and Affiliations
Shabnam Parveen, Deepa Arya
Keywords
Related Articles
- EP ID EP670581
- DOI 10.21276/ijlssr.2018.4.1.8
- Views 76
- Downloads 0
Association of Serum MMP 9 Level with COPD and Healthy Control in North Indian Population
- Background: Chronic Obstructive pulmonary disease (COPD) is an increasing cause of morbidity and mortality world-wide. MMP 9 is an acute phase reactant secreted by the liver in response to infection, inflammation or ti...
Gene Frequencies of Haemoglobin Genotype, ABO and Rhesus Blood Groups among Students Population of a Private University in Nigeria-Implications for Blood Banking
Background- ABO and Rhesus blood groups are the two most important blood group systems of clinical significance. ABO is classified into four major groups (A, B, AB and O), while Rhesus is classified as positive or negati...
Regeneration of Plantlets from Rhizome Bud Explants of Lasia spinosa (Lour.) Thwaites- A Medicinal Plants of Assam
In numerable medicinal plants are commercially propagated through tissue culture for large production of elite material (Rhizome buds of Lasia spinosa {Lour.}). Thwaites could be induced on Murashige and Skoog (MS) mediu...
Antimicrobial activity of Antibiotics and Antiseptics (Dettol and Betadine) against Clinical Isolates of Pseudomonas aeruginosa
Hundred samples viz. urine, blood, wound, pus and sputum collected from different patients were found to harbour Pseudomonas aeruginosa (P. aeruginosa) (27%) with a maximum isolation from wound samples (33.33%) and minim...
Genotoxic Study of Chewing Leaf Tobacco in Swiss Albino Mice
The tobacco plant Nicotiana has probably been responsible for more deaths than any other herb as it is market driven commodity of economic benefit. While the majority will likely be killed by use of cigarettes, tobacco u...