RECENT CHEMICAL ADVANCEMENTS OF PYRAZOLE MOIETY IN ANTICANCER THERAPY
Journal Title: International Journal of Engineering Sciences & Research Technology - Year 30, Vol 5, Issue 4
Abstract
Pyrazole moiety is one of the main scaffold for many anticancer drug candidates.Many pyrazole derivatives have been synthesized which shows their activity against different leukemia cell line, non-small cell lung cancer, colon cancer, prostate cancer, CNS cancer, renal cancer, breast cancer, ovarian cancer and cervix cancer cell line. Literature survey revealed that they have been implemented as antitumor, antileukemic and antiproliferative agent beside their capability to inhibit different types of enzymes which plays important roles in cell division.
Authors and Affiliations
Amrita Verma
Keywords
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- DOI 10.5281/zenodo.50425
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