Recent developments in atom transfer radical polymerization initiators for development of polymer-protein bioconjugates
Journal Title: Journal of BioScience and Biotechnology - Year 2013, Vol 2, Issue 1
Abstract
One of the major challenges in modern synthetic polymer chemistry is to synthesize end defined polymers of different end functionality with predetermined uniform molecular weight. End functionalized polymers/copolymers basically in block and grafting form are having several potential applications in biomedical areas in the form of surface modifications, coatings, adhesives, and in order to increase the biocompatibility of polymeric blends. Among the existing controlled radical polymerization (CRP) methods for synthesis of these functional polymers, the atom transfer radical polymerization (ATRP) is one of the powerful techniques. The functional groups in these polymers can be easily introduced at the chain ends through functionalized ATRP initiators. A number of ATRP initiators have been developed in polymer science to develop defined polymer-protein bioconjugates. This critical review basically focuses on different types of ATRP initiators and their mechanisms used in the synthesis of polymer-protein bioconjugates.
Authors and Affiliations
Akhilesh Shakya, Ashok Kumar
Keywords
Related Articles
- EP ID EP141005
- DOI -
- Views 91
- Downloads 0
Identification of the essential oils composition from four ecotypes of Mentha longifolia (L.) Huds. growing wild in Isfahan province, Iran
Mentha longifolia L., commonly known as wild mint, belongs to family Lamiaceae. The aim of this study was to identify the chemical composition of essential oil extracted from four ecotypes of Mentha longifolia L. g...
Effects of enzyme supplementation on replacing corn with barley in diet of broiler chicks
Two experiments were carried out to evaluate the effects of an enzyme complex (Agrozyme®, a cocktail of cellulolytic, amylolytic, and proteolytic enzymes) on barley energy content and its nutritive value for broiler chic...
Sibling vole species (Microtus) in the fragmented landscape of south-eastern part of Thrace, Balkan Peninsula: species presence, habitat selection and craniometry
The presence of sibling vole species (Microtus) in the most common forests and open landscapes in south-eastern part of Thrace (Balkan Peninsula) of contemporary territories of Bulgaria and Turkey was studied. Only...
In vitro fermentation of olive oil mill wastewaters using sheep rumen liquor as inoculum: Olive mill wastewaters an alternative for ruminant's nutrition
Olive oil mill wastewaters (OMWW) are the main liquid effluents generated by the olive oil production industry. This liquid, considered pollutant and toxic, is characterised by its high content of organic matter in...
Silver nitrate and chlorhexidine gluconate – effective surface sterilization agents in disinfection procedures at initiation of woody shoot tip and embryo culture
The surface sterilization of explants in chemical solutions is an important step to remove contaminants with minimal damage to plant cells. Woody and mature plants growing in the open field are known to harbor a large am...