Recent Developments in Diffusion Tensor Imaging of Brain
Journal Title: Radiology – Open Journal - Year 2016, Vol 1, Issue 1
Abstract
Magnetic Resonance Imaging (MRI) has come to be known as a unique radiological imaging modality because of its ability to perform tomographic imaging of body without the use of any harmful ionizing radiation. The radiologists use MRI to gain insight into the anatomy of organs, including the brain, while biomedical researchers explore the modality to gain better understanding of the brain structure and function. However, due to limited resolution and contrast, the conventional MRI fails to show the brain microstructure. Diffusion Tensor Imaging (DTI) harnesses the power of conventional MRI to deduce the diffusion dynamics of water molecules within the tissue and indirectly create a three-dimensional sketch of the brain anatomy. DTI enables visualization of brain tissue microstructure, which is extremely helpful in understanding various neuropathologies and neurodegenerative disorders. In this review, we briefly discuss the background and operating principles of DTI, followed by current trends in DTI applications for biomedical and clinical investigation of various brain diseases and disorders.
Authors and Affiliations
Mohammed Inayathullah
Evaluation of Whole Body DiffusionWeighted Imaging in the Staging and Treatment Response of Lymphoma Compared With Fluoride-Oxyglucose (FDG) PET/CT as a Reference Standard
Introduction: Positron emission tomography/computed tomography (PET/CT) is currently considered standard of practice for the management of lymphoma with sensitivity and specificity approaching 100%. However, it is expens...
Cerebral Blood Flow Assessment by Digital Subtraction Angiography
Cerebral vascular disease is responsible for nearly 800 000 hospital admissions annually with a total healthcare cost of $34 billion. Neuro-interventional surgery is at the forefront of fast-response assessment and inter...
An Attempt to Integrate Diffusion Weighted and Dynamic Contrast Enhanced MRI
Diffusion Weighted MRI (DWI) and Dynamic Contrast Enhanced MRI (DCE-MRI) are increasingly used for cancer assessment. Both modalities require adequate post-processing to extract useful information. DWI can be analyzed us...
Does Iterative Reconstruction Improve Image Quality and Reduce Dose in Computed Tomography?
The Filtered Back Projection (FBP) algorithm has been the standard algorithm for image reconstruction in computed tomography (CT) for many years, but it creates possible streak artifacts and a notable increase in image n...
Giant Peroneal Ganglion Cyst: Imaging and Clinical Findings
A ganglion cyst is the cystic lesion originates from the joint capsule or tendon sheath. This lesion is the most common soft tissue tumors of hand, wrist, and foot, and frequently observed in women between 30-50 years. A...