RECENT REPORTS ON PYRAZOLE-BASED BIOACTIVE COMPOUNDS AS CANDIDATE FOR ANTICANCER AGENTS
Journal Title: Asian Journal of Pharamceutical and Clinical Research - Year 2017, Vol 10, Issue 12
Abstract
  Pyrazole is a five-membered heterocyclic compound containing two nitrogen atoms. Due to its biological significance, design of novel pyrazole derivatives has become an interesting research area. We report the current progress in the development of anticancer agents containing pyrazole ring covering the time span of the past few years (2013–2016). The presence of this nucleus is accompanied with some side chains, functional groups, or in combination with other nucleus such as thiazole, thiourea, glucosamine, naphthalimide, and benzofuran. Several biologically active pyrazoles synthesized by numerous researchers across the world are summarized in this paper.
Authors and Affiliations
Bayu Ardiansah
Keywords
Related Articles
- EP ID EP605498
- DOI 10.22159/ajpcr.2017.v10i12.22065
- Views 106
- Downloads 0
FACTORS INFLUENCING COMPLIANCE TO THERAPEUTIC REGIMEN AMONG PATIENTS WITH HYPERTENSION
Objectives: The objectives of the study were to identify the level of compliance to therapeutic regimen, assess the factors promoting and interfering compliance, and to find the association between level of compliance an...
SANSEVIERIA HYACINTHOIDES (L.) DRUCE: A REVIEW OF ITS BOTANY, MEDICINAL USES, PHYTOCHEMISTRY, AND BIOLOGICAL ACTIVITIES
Sansevieria hyacinthoides is a succulent perennial herb widely used as herbal medicine. This study is aimed at providing a critical review of the botany, biological activities, phytochemistry, and medicinal uses of S. hy...
ORAL CYCLOSPORINE AS AN ALTERNATIVE FOR INITIAL STANDARD PROPHYLAXIS IN ALLOGENEIC STEM CELL TRANSPLANTATION WHEN INTRAVENOUS FORMULATION IS UNAVAILABLE
Objective: The objective of the study was to compare the incidence of acute graft versus host disease (aGVHD) between oral and intravenous (IV) initial standard cyclosporine A (CsA) prophylaxis in a tertiary care center...
GAS CHROMATOGRAPHY - MASS SPECTROMETRY ANALYSIS, INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY INVESTIGATION, AND ANTIMICROBIAL SCREENING OF CAESALPINIA BONDUCELLA (L.) ROXB SEED KERNEL
Objective: The objective of this study was to determine heavy metals using inductively coupled plasma mass spectrometry (ICP-MS) and phytochemical constituents of methanol extract of Caesalpinia bonducella seed kernel us...
SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF NOVEL 5-ARYLIDENE-2-IMINO-3-(2- PHENYL- 1,8-NAPHTHYRIDIN-3-YL)THIAZOLIDIN-4-ONES
Objectives: Nowadays, antimicrobial resistance represents one of the most significant challenges in the medical community. To overcome the problem, it requires the discovery of newer safe and effective molecules against...