RECHALLENGING TREATMENT PLAN FOR MULTIDRUG-RESISTANT TUBERCULOSIS IN DIABETIC PATIENT: A CASE REPORT
Journal Title: Asian Journal of Pharamceutical and Clinical Research - Year 2019, Vol 12, Issue 2
Abstract
Multidrug-resistant tuberculosis (MDR-TB) currently considers as the biggest issue and its subcategory, rifampicin-resistant TB (RR-TB). MDR-TB is defined as a resistant to isoniazid (H) and rifampicin (R), while the latter is resistant to rifampicin (R) only. Poorly controlled diabetes mellitus increases the risk of TB and leads to poor TB treatment outcomes as well it is consider potentially threating TB control. Difference in patients’ response and side effect developments toward anti-TB (ATB) medications requires rechallenging procedure that can be complicated at times. The management of MDR-TB can be complicated, especially, when the patient cannot tolerate the short regimen. Difference in patients’ response and side effect developments toward ATB medications requires rechallenging procedure which can have prolonged treatment time, hospital stay, and make patients exposed to hospital-acquired infection. This challenges and obstacles, however, could be prevented earlier by having strong DOTS strategy to prevent the development of resistance and reactivation of TB.
Authors and Affiliations
AHMED ALAA AL-TEMIMI, MUHAMMAD ZHARIF M NIZAM, YAHAYA HASSAN, NOORIZAN A AZIZ, MOHD FADLI MOHD ASMANI, IBRAHIM ABDULLAH
Keywords
Related Articles
- EP ID EP608726
- DOI 10.22159/ajpcr.2019.v12i2.24772
- Views 129
- Downloads 0
HEPATOPROTECTIVE EFFECT OF PERILLYL ALCOHOL (POH) ON HIGH-FAT DIET-LOW-DOSE STREPTOZOTOCIN-INDUCED TYPE 2 DIABETES IN EXPERIMENTAL RATS
Objective: The aim of the present study was to investigate the hepatoprotectivity effect of perillyl alcohol in high-fat diet (HFD)-low-dose streptozotocin (STZ)-induced diabetic rats. Methods: Diabetes was induced in m...
COMPARATIVE STUDY OF SPAN 40 AND SPAN 60 BASED SOY-GELS FOR TOPICAL DRUG DELIVERY
Objective: Hydrogels or emulgels are recommended for topical application to elicit a local effect. However, they suffer from stability problems. The present study deals with the formulation and comparison of thermally st...
FORMULATION AND INVESTIGATION OF POLYMERIC MULTIPLE UNIT PELLET SYSTEMS CONSISTING OF SUSTAINED RELEASE GLIMEPIRIDE AND IMMEDIATE RELEASE ATORVASTATIN CALCIUM
Objective: The objective of the present work was to develop novel fixed-dose combinations (FDCs) for improvement of glucose tolerance in type II diabetes mellitus patients associated with dyslipidemia. Methods: Multiple...
DEVELOPMENT AND IN VITRO EVALUATION OF PHYTOSOMES OF NARINGIN
Objective: Phytosomes are novel herbal formulations meant for design of poorly soluble flavonoids of therapeutic potential. Naringin is a flavanone with poor oral absorption and bioavailability but possess antioxidant, a...
TRYPANOCIDAL, ANTI-LEISHMANIAL, AND CYTOTOXIC ACTIVITY OF MUEHLENBECKIA TAMNIFOLIA (KUNTH) MEINS (POLYGONACEAE)
Objective: The objective of this study was to evaluate the activity against amastigotes of Leishmania panamensis and epimastigotes of Trypanosoma cruzi (Chagas), extracts and fractions obtained from leaves and stems of M...