Recombinant activated factor VII for refractory bleeding during pediatric spinal tumor surgery: A case report
Journal Title: Indian Journal of Case Reports - Year 2018, Vol 4, Issue 6
Abstract
Bleeding complications constitute a particular challenge in neurosurgical procedures especially in children and may be lifethreatening. We report the case of a 5-month-old boy to whom recombinant activated factor VII was given at doses of 90 μg/kg of body weight for the control of refractory perioperative bleeding during spinal neurofibromas surgery. Conventional treatment with fresh-frozen plasma, platelet concentrates, and fibrinogen concentrate failed to control hemorrhage. Recombinant activated factor administration resulted in decreased bleeding, hemodynamic stabilization, and improved surgical hemostasis.
Authors and Affiliations
Rebai Lotfi, Boussaidi Ines, Daghmouri Aziz, Ghader Ghassen
Keywords
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