Recreational physical activity is inversely associated with asymptomatic gallstones in adult Mexican women
Journal Title: Annals of Hepatology - Year 2014, Vol 13, Issue 6
Abstract
Background and rationale. Epidemiologic research suggests that physical activity (PA) reduces the risk of chronic diseases including gallstones. Objective. This study explores the association between recreational physical activity (RPA) and risk of asymptomatic gallstones (AG) in adult Mexican women. Material and methods. We performed a cross-sectional analysis of women from the Health Workers Cohort Study. The study population included Mexican women aged 17-94 years, with no history of gallstone (GS) or cholecystectomy. A self-administered questionnaire was used to collect information on weight change, gynecological health history, cholesterol-lowering medications and diuretics, history of diabetes mellitus type 2 (DM2), PA and diet. PA was calculated in minutes/day, minutes/week and Metabolic Equivalents (METs)/week. Gallstone diagnosis was performed using real-time ultrasonography. The association between RPA and risk of AG was evaluated using multivariate logistic regression models. Results. Of the 4,953 women involved in the study, 12.3% were diagnosed with AG. The participants with AG were significantly older, had a higher body mass index, and had a higher prevalence of DM2 than those without AG. The participants with > 30 min/day of RPA had lower odds of AG (OR = 0.80; 95% CI: 0.65-0.97; P = 0.03), regardless of other known risk factors for gallstone disease. Furthermore, we observed an inverse relationship between RPA time and AG risk, especially in women doing more than 150 min a week of RPA (OR = 0.76; 95%CI: 0.61- 0.95; P = 0.02). Conclusion. These findings support the hypothesis that RPA may protect against AG, although further prospective investigations are needed to confirm this association.
Authors and Affiliations
Santiago Henao-Morán, Edgar Denova-Gutiérrez, Segundo Morán, Ximena Duque, Katia Gallegos-Carrillo, Nayeli Macías, Jorge Salmerón
Keywords
Related Articles
- EP ID EP78458
- DOI -
- Views 150
- Downloads 0
The CT Quadrate lobe hot spot sign
Intense enhancement of the quadrate lobe in the arterial phase may be seen on computed tomography in patients of superior vena cava syndrome. We present this imaging finding in a case of lymphoma causing superior vena ca...
Human leukocyte antigens among primary biliary cirrhosis patients born in Mexico
Background and aim: Primary biliary cirrhosis (PBC) is a chronic cholestatic disease of autoimmune origin and has a genetic component. Although it has been reported that the prevalence of the HLA-DRB1*08 allele is high i...
Prevalence of hepatitis C virus infection among patients undergoing haemodialysis in Latin America
Hepatitis C infection is a worldwide problem. The global prevalence of the hepatitis C virus (HCV) averages 3%. Moreover, its prevalence among patients undergoing haemodialysis (HD) varies worldwide, ranging from as low...
Clinical course and management of acute hepatitis A infection in adults
Background. Hepatitis A is the most common type of viral hepatitis in Mexico. The change of hepatitis A epidemiology in Mexico from high to intermediate endemicity leads to increasing susceptible adults for severe illn...
Prevalence of hepatitis A, B and C serological markers in children from western Mexico
Introduction. Viral hepatitis in children is a major public health problem worldwide. Aim. To evaluate the prevalence of serological markers for hepatitis A, B and C infections in Mexican children diagnosed with hepatiti...