Rectal Versus Intramuscular Diclofenac Sodium for Pain Relief Following Caesarean Section: A Randomised Controlled Trial
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 8
Abstract
Introduction: Patients who undergo caesarean delivery should have adequate postoperative pain relief so as to ensure maternal and neonatal wellbeing. Management of postoperative pain after caesarean section requires a balance between pain relief and undesirable side effects of drugs and route of administration. This study was designed to compared the analgesic efficacy of rectal diclofenac and intramuscular diclofenac for pain relief following caesarean section. Method: A total number of sixty six (66) patients undergoing elective lower segment caesarean delivery under spinal anaesthesia were randomized into two groups. Thirty-three (33) patients in each group received either 100mg of rectal diclofenac sodium or 75mg of intramuscular diclofenac sodium for duration of 24 hours, following caesarean section. Results: Fewer patients in the rectal arm had rescue analgesia,12(42.86%) vs 16(57.14%), P=0.21. The number of rescue analgesia was also lower in the rectal group, 16(41.03%) vs 23(58.97%), P=0.027. The time interval between commencement of post-operative analgesia and demand for rescue analgesic agent was similar in both group 4.28 ± 2.78 hours and 3.98 ± 2.52 hours respectively, P=0.77. The pain scores were higher in the intramuscular diclofenac group at 6, 12, 18 and 24 hours post operation. Side effects occur more frequently in the intramuscular group than in the rectal group but patients' satisfaction was similar in both groups, rectal (84.8%) and intramuscular (78.8%), P=0.612. Conclusion: Both routes of administration demonstrate good pain control, however rectal route appears more tolerable among the patients.
Authors and Affiliations
Adeniyi Augustine Adebayo
Assessment of Selected Heavy Metals in Soil and Untreated Wastewater Used For Irrigation in Urban and Peri-Urban Farms in Eastern Nairobi City County, Kenya
Introduction: Untreated wastewater contains heavy metals harmful to human health and the environment. People get access to untreated water through broken sewer pipes, blocked manholes and direct disposal into rivers. One...
Profile of type-2 diabetes mellitus with and without complications
Objective: To describe the profile of type-2 diabetes patients. Methods: This was a cross-sectional study conducted in tertiary care hospital. A total of 50 cases of diabetes with and without complication with 35-75 year...
Collision Tumor of Thyroid: A Rare Case Report
Abstract
Infertility – A Social Stigma in Kashmir
According to the International Committee for Monitoring Assisted Reproductive Technology and the World Health Organization, infertility is a disease of the reproductive system defined by the failure to achieve a clinical...
Ecopharmacovigilance
In this article we have presented some ideas on what Ecopharmacovigilance (EPV) might mean in practice, together with what challenges and opportunities it poses in today’s scenario implementing EPV procedures.