Red Blood Cells Morphological Changes as a Prognostic Tool for Organophosphorus Toxicity Patients
Journal Title: Journal of Medical Science And clinical Research - Year 2015, Vol 3, Issue 7
Abstract
Aims & Objectives- Identify and exclude the misinterpretation of peripheral blood smears examination. Identify organophosphorus induced RBC & WBC morphological changes used as a prognostic tool. Identify the organophosphorus induced peripheral blood cells changes. Material & Methods: Blood was collected in a sterile EDTA containing tube and processed following our established laboratory protocol. A complete blood counting including HB%, PCV, Red cell indices, platelet count and total white cell count and differential was done by Automated blood cell counter with peripheral blood smear examination and further confirmed by manual oil immersion smear study method. Peripheral smears study was done with field A and B stain and leishman stain. Conclusion- organophosphorus can cause changes on peripheral blood cell due to lipid peroxydation and oxidative stress of cell membrane. RBC shows various types changes theses may be used as a prognostic tool for severity of toxicity, monitoring of patients and follow-up and exclude the various misinterpretation of peripheral blood smear examination like hemolytic anemia and liver disease.
Authors and Affiliations
Dr. O. P. Moorjani
Keywords
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