Red cell distribution width and mortality in pediatric sepsis
Journal Title: Paediatrica Indonesiana - Year 2016, Vol 56, Issue 6
Abstract
Background Red cell distribution width (RDW) is a hematological parameter routinely obtained as part of the complete blood count. Recently, RDW has emerged as a potential independent predictor of clinical outcomes in adults with sepsis. However, RDW as a mortality predictor in pediatric populations has not been well established.Objective To determine the relationship between RDW value and mortality outcomes in pediatric sepsis patients.Methods We performed a cross-sectional study of 40 consecutive pediatric patients with sepsis admitted to the PICU from December 2013 to March 2014. All patients’ RDW were collected within 24 hours of sepsis diagnosis. We determined the association between RDW and hemoglobin (Hb) using Spearman’s correlation. The RDW values of 11.5-14.5% were considered to be normal while those > 14.5% were considered to be elevated. We compared mortality and PICU length of stay (LoS) between the normal and elevated RDW groups using Chi-square and Mann-Whitney tests.Results The median age of patients was 34 months (range 2 months to 17 years). There were 28 (70%) male subjects. Subjects’ median RDW was 14.8% (range 11.2-27.8%) and was not correlated with Hb (r=0.056; P=0.73). Mortality rates in the normal and elevated RDW groups were 40% and 45%, respectively. There were no significant associations between RDW group and mortality (P=0.749) or PICU LoS (P=0.350).Conclusion Unlike in adults, RDW values are not correlated with mortality in pediatric sepsis patients.
Authors and Affiliations
Trina Devina, Munar Lubis, Erna Mutiara, Gema Yanni, Rina Saragih, Yunnie Trisnawati, Aridamuriany Lubis, Putri Amelia
Keywords
Related Articles
- EP ID EP446160
- DOI 10.14238/pi56.6.2016.320-4
- Views 74
- Downloads 0
Consumption of energy-dense, nutrient-poor foods and hypertension in obese children
Background Obesity has become an increasingly important medicalproblem in children. Obesity-induced hypertension in childhoodshould be considered as a chronic medical condition that is likelyto require long-term manageme...
Noise exposure at school and blood pressure in adolescents
Background The increasing prevalence of primary hypertension has motivated researchers to identify influencing factors, one of which is noise. There have been few studies on a relationships between noise exposure and blo...
Habitual snoring and primary enuresis in children
Background Obstructive sleep-disordered breathing is assumed to be associated with primary enuresis in children. Prolonged enuresis may cause developmental and emotional disorders, as well as poor school performance. Ob...
Low serum zinc and short stature in children
Background Short stature/stunting is common in developing countries, and has been used as an indicator of a nation’s general health condition. Short stature increases the risk of metabolic disease, disturbances in cognit...
Side effect of deferiprone as iron chelator in patient with thalassemia
Background There are currently three available iron chelators: deferoxamine (DFO), deferasirox (DFX) and deferiprone (DFP). In Dr. Cipto Mangunkusumo Hospital and Indonesia, in general, the accessibility of DFP for thala...