Red Cell Distribution Width Predicts the Left Ventricular Reverse Remodeling After ST Segment Elevation Myocardial Infarction Undergone Primary Percutaneous Coronary Intervention
Journal Title: E Journal of Cardiovascular Medicine - Year 2020, Vol 8, Issue 2
Abstract
Objectives: Previous studies have shown that red blood cell distribution width (RDW) is associated with some cardiac diseases. We investigated whether RDW was associated with left ventricular (LV) reverse remodeling after ST segment elevation myocardial infarction. Materials and Methods: This retrospective study analyzed 300 patients with ST segment elevation myocardial infarction who underwent a follow-up echocardiography. We recorded the clinical characteristics, laboratory values and echocardiographic signs of the patients on admission and in the third month. The patients were categorized into two groups according to echocardiographic assessment after 3 months: LV reverse remodeling and non-reverse remodeling. Results: The RDW levels were significantly lower in the patients who had LV reverse remodeling than the patients who had non-reverse remodeling (15.4±2 vs 17.8±3.6, p<0.001). In the multivariate logistic regression analysis, the independent predictors of reverse remodeling were Diabetes Mellitus (p=0.001), history of coronary artery bypass grafting surgery (p=0.031), ST segment resolution (p=0.021), Thrombolysis in myocardial infarction flow classification (p=0.023) and RDW level (p<0.001). According to the receiver operating characteristic curve analysis, it was found that RDW (for the 17.3 level) had an estimate for LV reverse remodeling. Conclusion: We suggest that the RDW level that is counted during routine complete blood count test might be useful to estimate LV reverse remodeling.
Authors and Affiliations
Pınar Demir Gündoğmuş, Kamuran Kalkan, Remziye Doğan, Abdulkadir Uslu, Enbiya Aksakal
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